Evidence map›Paper›PMID 37794011›Full record

ArticleNature communications2023

Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1.

Jing Xue, Weizhong Zeng, Yan Han, Scott John, Michela Ottolia, Youxing Jiang

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. The NaThe Journal of veterinary medical science · 2026
    Review
  3. Article
  4. Molecular mechanisms of mitochondrial CaNature communications · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Molecular mechanisms of mitochondrial CabioRxiv : the preprint server for biology · 2026
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Inter-Organellar CaCells · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jing XueHoward Hughes Medical Institute and Department of Physiology, The University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-7331-1382
Weizhong ZengHoward Hughes Medical Institute and Department of Physiology, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
Yan HanHoward Hughes Medical Institute and Department of Physiology, The University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-1207-7756
Scott JohnDepartment of Medicine (Cardiology), David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-1232-9140
Michela OttoliaDepartment of Anesthesiology and Perioperative Medicine, Division of Molecular Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Youxing JiangHoward Hughes Medical Institute and Department of Physiology, The University of Texas Southwestern Medical Center, Dallas, TX, USA. youxing.jiang@utsouthwestern.edu.ORCID http://orcid.org/0000-0002-1874-0504
Howard Hughes Medical Institute · USUniversity of California, Los Angeles · US

Funding

Sodium Dependent Inactivation of the Na+-Ca2+ exchange: Relevance to Cardiac FunctionR01HL152296 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OLCESE, RICCARDO, OTTOLIA, MICHELA · 2021 to 2024
$2.2M
Structural and Functional Studies of Organellar Ion ChannelsR35GM140892 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI JIANG, YOUXING · 2021 to 2025
$1.6M
The Cardiac Na-Ca exchanger: Defining the mechanisms of its operation and regulationR01HL130308 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OTTOLIA, MICHELA · 2016 to 2019
$1.6M
Howard Hughes Medical InstituteNHLBI NIH HHS R01 HL130308NHLBI NIH HHS R01 HL152296NIGMS NIH HHS R35 GM140892
6 · The paper itself

Abstract

Na

Indexed as

HeartSodium-Calcium ExchangerCalciumCytosolHumansIon TransportCalciumSodium-Calcium Exchanger

Identifiers

PMID37794011
PMCPMC10550945
OpenAlexW4387333055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.