Trial reportJournal of neurointerventional surgery2024
Evaluation of effectiveness and safety of the CorPath GRX robotic system in endovascular embolization procedures of cerebral aneurysms.
Trial report in Journal of neurointerventional surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04236856 (An Evaluation of Effectiveness and Safety of the CorPath® GRX System in Endovascular Embolization Procedures of Cerebral Aneurysms), which is not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Evaluation of Effectiveness and Safety of the CorPath® GRX System in Endovascular Embolization Procedures of Cerebral Aneurysms
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Robot-assisted versus manual percutaneous vascular interventions across vascular territories: a systematic review and meta-analysis.Journal of robotic surgery · 2026Pooled it
- Evaluating the CorPath GRX robotic system in cerebral aneurysm embolization and diagnostic angiography: a systematic review and single-arm meta-analysis.Journal of robotic surgery · 2026Pooled it
- In the era of transition from fiction to reality: Robotic-assisted neurointervention-a systematic review and meta-analysis.Neurosurgical review · 2024Pooled it
- Bibliometric and knowledge-map analysis of research on robot-assisted vascular interventional surgery (2015-2025).Journal of robotic surgery · 2026Article
- Global trends and emerging frontiers in robot-assisted vascular intervention: a comprehensive bibliometric analysis.Journal of robotic surgery · 2026Review
- Current State and Future of Artificial Intelligence in Pediatric Interventional Radiology: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Evaluation of Fully Teleoperated Robotic Endovascular Interventions with Haptic Feedback: The SENTANTE Endovascular Robotic System.Cardiovascular and interventional radiology · 2026Article
- Clinical validation and literature review of robot-assisted cerebral angiography.Chinese neurosurgical journal · 2026Article
- Advancements and challenges in autonomous endovascular interventional robotics: A comprehensive review.iScience · 2025Review
- Emerging Techniques and Treatment Outcomes in Pulmonary Arteriovenous Malformations Embolisation: A Narrative Review.Journal of clinical medicine · 2025Review
- Impact of Image Latency and Frame Rate on Simulated Remote Robotic-Assisted Neurovascular Procedures.AJNR. American journal of neuroradiology · 2025Article
- Robotic Stroke Thrombectomy: A Feasibility and Efficacy Study in Flow Models.Journal of stroke · 2025Article
- Haptic feedback in robotic endovascular neurosurgical intervention: A necessity or a commodity?Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Can micro-guidewire advancement forces predict clot consistency and location to assist the first-line technique for mechanical thrombectomy?Journal of neurointerventional surgery · 2025Article
- Robotic Systems in Cardiovascular Interventions: Evolving Platforms and the Path Forward.Methodist DeBakey cardiovascular journal · 2025Review
- Artificial Intelligence in Neuroendovascular Procedures.Journal of neuroendovascular therapy · 2025Review
- Robotics for Neuroendovascular Therapy.Journal of neuroendovascular therapy · 2025Review
- The Fusion of Robotics and Imaging: A Vision of the Future.Methodist DeBakey cardiovascular journal · 2025Review
- Flow Diversion for Endovascular Treatment of Intracranial Aneurysms: Past, Present, and Future Directions.Journal of clinical medicine · 2024Review
- Modeling Robotic-Assisted Mechanical Thrombectomy Procedures with the CorPath GRX Robot: The Core-Flow Study.AJNR. American journal of neuroradiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 12 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRobotic-assisted neurointervention was recently introduced, with implications that it could be used to treat neurovascular diseases.
objectiveTo evaluate the effectiveness and safety of the robotic-assisted platform CorPath GRX for treating cerebral aneurysms.
methodsThis prospective, international, multicenter study enrolled patients with brain aneurysms that required endovascular coiling and/or stent-assisted coiling. The primary effectiveness endpoint was defined as successful completion of the robotic-assisted endovascular procedure without any unplanned conversion to manual treatment with guidewire or microcatheter navigation, embolization coil(s) or intracranial stent(s) deployment, or an inability to navigate vessel anatomy. The primary safety endpoint included intraprocedural and periprocedural events.
resultsThe study enrolled 117 patients (74.4% female) with mean age of 56.6 years from 10 international sites,. Headache was the most common presenting symptom in 40/117 (34.2%) subjects. Internal carotid artery was the most common location (34/122, 27.9%), and the mean aneurysm height and neck width were 5.7±2.6 mm and 3.5±1.4 mm, respectively. The overall procedure time was 117.3±47.3 min with 59.4±32.6 min robotic procedure time. Primary effectiveness was achieved in 110/117 (94%) subjects with seven subjects requiring conversion to manual for procedure completion. Only four primary safety events were recorded with two intraprocedural aneurysm ruptures and two strokes. A Raymond-Roy Classification Scale score of 1 was achieved in 71/110 (64.5%) subjects, and all subjects were discharged with a modified Rankin Scale score of ≤2.
conclusionsThis first-of-its-kind robotic-assisted neurovascular trial demonstrates the effectiveness and safety of the CorPath GRX System for endovascular embolization of cerebral aneurysm procedures. TRIAL REGISTRATION NUMBER: NCT04236856.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.