Evidence map›Paper›PMID 37793695›Full record

ArticleBMJ (Clinical research ed.)2023

Interactive effects of ambient fine particulate matter and ozone on daily mortality in 372 cities: two stage time series analysis.

Cong Liu, Renjie Chen, Francesco Sera, Ana Maria Vicedo-Cabrera, Yuming Guo, Shilu Tong, Eric Lavigne, Patricia Matus Correa, Nicolás Valdés Ortega, Souzana Achilleos and 25 more

Abstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Differential impacts of short-term PMScience China. Life sciences · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Ambient PMBMC public health · 2025
    Article
  12. Foreseeable Co-occurring OACS environmental Au · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors.

Cong LiuSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China.
Renjie ChenSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China.
Francesco SeraDepartment of Statistics, Computer Science and Applications "G. Parenti," University of Florence, Florence, Italy.
Ana Maria Vicedo-CabreraInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Yuming GuoDepartment of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Shilu TongNational Institute of Environmental Health, Chinese Centre for Disease Control and Prevention, Beijing, China.
Eric LavigneSchool of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Patricia Matus CorreaDepartment of Public Health, Universidad de los Andes, Santiago, Chile.
Nicolás Valdés OrtegaDepartment of Public Health, Universidad de los Andes, Santiago, Chile.
Souzana AchilleosDepartment of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.
Dominic RoyeClimate Research Foundation, Madrid, Spain.
Jouni Jk JaakkolaCentre for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland.
Niilo RytiCentre for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland.
Mathilde PascalSanté Publique France, Department of Environmental and Occupational Health, French National Public Health Agency, Saint Maurice, France.
Alexandra SchneiderInstitute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg, Germany.
Susanne BreitnerInstitute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg, Germany.
Alireza EntezariClimate, Air Quality Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Fatemeh MayvanehFaculty of Geography and Environmental Sciences, Hakim Sabzevari University, Sabzevar, Khorasan Razavi, Iran.
Raanan RazBraun School of Public Health and Community Medicine, Hebrew University of Jerusalem, Israel.
Yasushi HondaCentre for Climate Change Adaptation, National Institute for Environmental Studies, Tsukuba, Japan.
Masahiro HashizumeDepartment of Global Health Policy, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Chris Fook Sheng NgSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Vânia GaioDepartment of Environmental Health, Instituto Nacional de Saúde Dr. Ricardo Jorge, Lisbon, Portugal.
Joana MadureiraDepartment of Environmental Health, Instituto Nacional de Saúde Dr. Ricardo Jorge, Lisbon, Portugal.
Iulian-Horia HolobacaFaculty of Geography, Babes-Bolay University, Cluj-Napoca, Romania.
Aurelio TobiasSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Carmen ÍñiguezConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Yue Leon GuoEnvironmental and Occupational Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.
Shih-Chun PanNational Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan.
Pierre MasselotDepartment of Public Health Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Michelle L BellSchool of the Environment, Yale University, New Haven, CT, USA.
Antonella ZanobettiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Antonio GasparriniDepartment of Public Health Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Haidong KanSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China kanh@fudan.edu.cn.ORCID 0000-0002-1871-8999

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

objectiveTo investigate potential interactive effects of fine particulate matter (PM

designTwo stage time series analysis.

setting372 cities across 19 countries and regions. POPULATION: Daily counts of deaths from all causes, cardiovascular disease, and respiratory disease.

main outcome measureDaily mortality data during 1994-2020. Stratified analyses by co-pollutant exposures and synergy index (>1 denotes the combined effect of pollutants is greater than individual effects) were applied to explore the interaction between PM

resultsDuring the study period across the 372 cities, 19.3 million deaths were attributable to all causes, 5.3 million to cardiovascular disease, and 1.9 million to respiratory disease. The risk of total mortality for a 10 μg/m

conclusionThe findings of this study suggest a synergistic effect of PM

Indexed as

Air PollutantsAir PollutionCardiovascular DiseasesEnvironmental PollutantsOzoneRespiration DisordersRespiratory Tract DiseasesCitiesEnvironmental ExposureHumansParticulate MatterTime FactorsAir PollutantsEnvironmental PollutantsOzoneParticulate Matter

Identifiers

PMID37793695
PMCPMC10548261

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.