Evidence map›Paper›PMID 37793495›Full record

ArticleExperimental eye research2023

A simplified protocol to induce hypoxia in a standard incubator: A focus on retinal cells.

Bhavneet Kaur, Bruna Miglioranza Scavuzzi, Steven F Abcouwer, David N Zacks

Open access · greenAbstract read
In one paragraph

Article in Experimental eye research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. A Differentiated SH-SY5Y Model of Hypoxic-Ischaemic Injury Reveals Dynamic Transcriptomic Responses During Reoxygenation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bhavneet KaurDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: bhka@med.umich.edu.
Bruna Miglioranza ScavuzziDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: bmiglior@med.umich.edu.
Steven F AbcouwerDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: sabcouwe@med.umich.edu.
David N ZacksDepartment of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: davzacks@med.umich.edu.
University of Michigan · US

Funding

VIVARIUM MODULEP30EY007003 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI David Antonetti · 1987 to 2026
$17.6M
TRAINING OF ARTHRITIS RESEARCH SCIENTISTST32AR007080 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jason Knight · 1986 to 2026
$6.3M
Molecular Regulation of Photoreceptor Cell DeathR01EY020823 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ABCOUWER, STEVEN F, ZACKS, DAVID N · 2010 to 2023
$5.0M
Inflammatory Resolution and Vascular Restoration in Diabetic RetinopathyR01EY029349 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ABCOUWER, STEVEN F, ANTONETTI, DAVID · 2018 to 2022
$2.4M
Role of mTORC1 in Retinal Ganglion Cell Physiology and DiseaseR01EY031961 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ABCOUWER, STEVEN F, FORT, PATRICE E. · 2020 to 2023
$2.1M
NEI NIH HHS P30 EY007003NEI NIH HHS R01 EY020823NEI NIH HHS R01 EY029349NEI NIH HHS R01 EY031961NIAMS NIH HHS T32 AR007080
6 · The paper itself

Abstract

Hypoxia chambers have traditionally been used to induce hypoxia in cell cultures. Cellular responses to hypoxia can also be mimicked with the use of chemicals such as cobalt chloride (CoCl

Indexed as

CobaltHypoxiaCell HypoxiaCell LineHumansHypoxia-Inducible Factor 1, alpha SubunitOxygenCobaltcobaltous chlorideHypoxia-Inducible Factor 1, alpha SubunitOxygenCobalt chlorideHypoxia chamberHypoxia-inducible factorRetina

Identifiers

PMID37793495
PMCPMC10732591
OpenAlexW4387252714

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.