Evidence map›Paper›PMID 37793287›Full record

ArticleJournal of the neurological sciences2023

The Queen Square Encephalitis Multidisciplinary Team Meeting - experience over three years, pre and post the COVID-19 pandemic.

Tehmina Bharucha, Rachel L Brown, Cristina Marcoci, Laura Benjamin, Chandrashekar Hoskote, Patricia McNamara, Jennifer Spillane, Michael S Zandi, Hadi Manji, Queen Square Encephalitis MDT Working Group

Abstract read
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In one paragraph

Article in Journal of the neurological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tehmina BharuchaNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Rachel L BrownNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK; University College London, Queen Square Institute of Neurology, London WC1N 3BG, UK; UCL Institute of Immunity and Transplantation, London NW3 2PP, UK.
Cristina MarcociNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.
Laura BenjaminNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK; UCL Laboratory of Molecular and Cell Biology, London WC1E 6BT, UK.
Chandrashekar HoskoteNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK; Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London WC1N 3BG, UK.
Patricia McNamaraNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.
Jennifer SpillaneNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.
Michael S ZandiNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK; University College London, Queen Square Institute of Neurology, London WC1N 3BG, UK.
Hadi ManjiNational Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK; University College London, Queen Square Institute of Neurology, London WC1N 3BG, UK. Electronic address: hadi.manji@nhs.net.
Queen Square Encephalitis MDT Working Group

Funding

Medical Research Council MR/T001313/1Wellcome Trust
6 · The paper itself

Abstract

backgroundPatients with suspected encephalitis continue to represent a diagnostic and therapeutic challenge, even in highly resourced centres. In February 2018, we set up a monthly in-person multidisciplinary team meeting (MDT). We describe the experience and outcomes of the MDT over three years.

methodsA retrospective analysis was performed to summarise patient demographics, MDT outcomes and final diagnoses.

resultsOver the three-year period, 324 discussions of 238 patients took place. Cases were diverse; approximately 40% related to COVID-19 or brain infection, 40% autoimmune or other inflammatory disorders and 20% encephalitis mimics or uncertain aetiologies. Feedback from an online survey sent to referring teams and attendees highlighted the value of the MDT; 94% reported the discussion was useful and 69% reported resulting change in patient management.

conclusionsMultidisciplinary input is crucial in this challenging area, ensuring that all diagnostic avenues are explored and opening doors to novel diagnostics and therapeutics. It also supports clinicians dealing with unwell patients, including in centres where less specialist input is available, and when decisions have to be made where there is little or no evidence base.

Indexed as

COVID-19EncephalitisHumansPandemicsPatient Care TeamRetrospective StudiesAutoimmune diseaseEncephalitisMeningitisMultidisciplinary teamMyelitisNeurological infections

Identifiers

PMID37793287
PMCPMC10951958

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.