Evidence map›Paper›PMID 37792730›Full record

ArticlePloS one2023

Assessment of glycemic variability and lifestyle behaviors in healthy nondiabetic individuals according to the categories of body mass index.

Kazuhiro Kashiwagi, Jun Inaishi, Shotaro Kinoshita, Yasuyo Wada, Sayaka Hanashiro, Kiko Shiga, Momoko Kitazawa, Shiori Tsutsumi, Hiroyuki Yamakawa, Junichiro Irie and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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  8. Continuous Glucose Monitoring for Prediabetes: What Are the Best Metrics?Journal of diabetes science and technology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Kazuhiro KashiwagiHills Joint Research Laboratory for Future Preventive Medicine and Wellness, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-6301-1466
Jun InaishiCenter for Preventive Medicine, Keio University School of Medicine, Tokyo, Japan.
Shotaro KinoshitaHills Joint Research Laboratory for Future Preventive Medicine and Wellness, Keio University School of Medicine, Tokyo, Japan.
Yasuyo WadaCenter for Preventive Medicine, Keio University School of Medicine, Tokyo, Japan.
Sayaka HanashiroDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Kiko ShigaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Momoko KitazawaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Shiori TsutsumiGraduate School of Health Management, Keio University, Kanagawa, Japan.
Hiroyuki YamakawaCenter for Preventive Medicine, Keio University School of Medicine, Tokyo, Japan.
Junichiro IrieDivision of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0003-2662-4121
Taishiro KishimotoHills Joint Research Laboratory for Future Preventive Medicine and Wellness, Keio University School of Medicine, Tokyo, Japan.
Keio University · JPNorthwell Health · USTokyo University of Information Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are limited data about the association between body mass index (BMI), glycemic variability (GV), and life-related factors in healthy nondiabetic adults.

methodsThis cross-sectional study was carried out within our ethics committee-approved study called "Exploring the impact of nutrition advice on blood sugar and psychological status using continuous glucose monitoring (CGM) and wearable devices". Prediabetes was defined by the HbA1c level of 5.7-6.4% and /or fasting glucose level of 100-125 mg/dL. Glucose levels and daily steps were measured for 40 participants using Free Style Libre and Fitbit Inspire 2 under normal conditions for 14 days. Dietary intakes and eating behaviors were assessed using a brief-type self-administered dietary history questionnaire and a modified questionnaire from the Obesity Guidelines.

resultsAll indices of GV were higher in the prediabetes group than in the healthy group, but a significant difference was observed only in mean amplitude of glycemic excursions (MAGE). In the multivariate analysis, only the presence of prediabetes showed a significant association with the risk of higher than median MAGE (Odds, 6.786; 95% CI, 1.596-28.858; P = 0.010). Additionally, the underweight (BMI < 18.5) group had significantly higher value in standard deviation (23.7 ± 3.5 vs 19.8 ± 3.7 mg/dL, P = 0.038) and coefficient variability (22.6 ± 4.6 vs 18.4 ± 3.2%, P = 0.015), compared to the normal group. This GV can be partially attributed to irregularity of eating habits. On the contrary, the overweight (BMI ≥ 25) group had the longest time above the 140 or 180 mg/dL range, which may be due to eating style and taking fewer steps (6394 ± 2337 vs 9749 ± 2408 steps, P = 0.013).

conclusionsConcurrent CGM with diet and activity monitoring could reduce postprandial hyperglycemia through assessment of diet and daily activity, especially in non- normal weight individuals.

Indexed as

Diabetes Mellitus, Type 2Prediabetic StateAdultBlood GlucoseBlood Glucose Self-MonitoringBody Mass IndexCross-Sectional StudiesGlycated HemoglobinHumansLife StyleBlood GlucoseGlycated Hemoglobin

Identifiers

PMID37792730
PMCPMC10550127
OpenAlexW4387331600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.