ArticleOphthalmology and therapy2023
Optic Nerve Head Changes Measured by Swept Source Optical Coherence Tomography and Angiography in Patients with Intracranial Hypertension.
Article in Ophthalmology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.
- Exploring the utility of retinal optical coherence tomography as a biomarker for idiopathic intracranial hypertension: a systematic review.Journal of neurology · 2024Pooled it
- Retinal and choroidal changes in young adults during near work and eye closure measured by wide-field OCTA.BMC ophthalmology · 2026Article
- Retinal thickness is indicative of visual loss in patients with occipital lobe infarction.Frontiers in neurology · 2025Article
- Decreased Choroidal Vascular Index in Idiopathic Intracranial Hypertension.Brain and behavior · 2025Observational
- Noninvasive Bedside Approaches for Assessing Microvascular Dysfunction.Journal of vascular research · 2025Review
- Intracranial pressure affects retinal venular complexity in idiopathic intracranial hypertension: a retrospective observational study.BMC neurology · 2024Observational
- Macular exudate in idiopathic intracranial hypertension affects outer retina and visual acuity.BMJ open ophthalmology · 2024Article
- When Headache Is Not Just Headache: Two Years of Symptoms and the Value of Ophthalmic Awareness in Undiagnosed Idiopathic Intracranial Hypertension - A Case Report.Case reports in ophthalmologyArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
introductionThis study explored the structural and microvascular changes in the optic nerve head (ONH) of patients with intracranial hypertension (IH) by using swept-source optical coherence tomography (SS-OCT)/OCT angiography (OCTA) and evaluated their association with clinical features.
methodsThe optic disc morphology, peripapillary retinal nerve fiber layer (pRNFL), ganglion cell-inner plexiform layer (GCIPL), and microvascular densities of the nerve fiber layer plexus (NFLP), superficial vascular plexus (SVP), intermediate capillary plexus (ICP), and deep capillary plexus (DCP) were measured by the SS-OCT/OCTA tool. Frisen score, visual acuity, and intracranial pressure were assessed and recorded in patients with IH.
resultsSixty-one patients with IH and 65 controls were included in this study. Patients with IH showed thicker pRNFL and GCIPL thickness with larger ONH rim area when compared to controls (P < 0.001). Microvascular densities were increased in NFLP while densities were reduced in SVP, ICP, and DCP when compared to controls (P < 0.001). Structural thickness and microvascular densities were significantly correlated with Frisen scores (P < 0.05) and intracranial pressure (P < 0.05) in patients with IH.
conclusionStructural and microvasculature variations of the ONH were found in patients with IH compared to controls. Importantly, we showed that structural and microvascular changes in the ONH were correlated with their Frisen score and intracranial pressure in patients with IH.
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