Evidence map›Paper›PMID 37792218›Full record

ArticleNeurology and therapy2023

Consensus-Based Recommendations on the Use of CGRP-Based Therapies for Migraine Prevention in the UAE.

Taoufik Alsaadi, Deeb M Kayed, Abubaker Al-Madani, Ali Mohamed Hassan, Alessandro Terruzzi, Derk Krieger, Naji Riachi, Pournamy Sarathchandran, Suhail Al-Rukn

Open access · goldAbstract read
In one paragraph

Article in Neurology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Taoufik AlsaadiDepartment of Neurology, American Center for Psychiatry and Neurology, Abu Dhabi, UAE. talsaadi@live.ca.ORCID http://orcid.org/0000-0002-7513-5706
Deeb M KayedNeurology Department, Mediclinic City Hospital, Dubai, UAE.
Abubaker Al-MadaniNeurology Department, Rashid Hospital, Dubai, UAE.
Ali Mohamed HassanNeurology Department, Rashid Hospital, Dubai, UAE.
Alessandro TerruzziNeurology Department, Mediclinic City Hospital, Dubai, UAE.
Derk KriegerNeurology Department, Mediclinic Parkview Hospital, Dubai, UAE.
Naji RiachiSheikh Shakhbout Medical City, Khalifa University College of Medicine and Health Sciences, Abu Dhabi, UAE.
Pournamy SarathchandranAl Qassimi Hospital, Ministry of Health, Sharjah, UAE.
Suhail Al-RuknNeurology Department, Rashid Hospital, Dubai, UAE.
Mediclinic City Hospital · AERashid Hospital · AEAbu Dhabi University · AEKhalifa University of Science and Technology · AEMinistry of Health · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMigraine is a common debilitating neurological disorder affecting a large proportion of the general population. Calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide, plays a key role in the pathophysiology of migraine, and the development of therapies targeting the anti-CGRP pathway has revolutionized the field of migraine treatment.

methodsAn expert task force of neurologists in the United Arab Emirates (UAE) developed and critically assessed recommendations on the use of CGRP-based therapies in migraine treatment and management in the UAE, based on available published literature. A consensus was reached for each statement by means of an open-voting process, based on a predefined agreement level of at least 60%.

resultsThe consensus recommendations advocate the need for guidelines for the appropriate use of CGRP-based therapies by defining patient cohorts and appropriate monitoring of therapeutic response as well as standardizing the initiation, assessment, and cessation of treatment. The consensus recommendations were primarily formulated on the basis of international studies, because of the limited availability of regional and local data. As such, they may also act as guidelines for global healthcare providers.

conclusionsThese are the first consensus recommendations for the UAE that address the use of CGRP-based therapies in the treatment and management of migraine, integrating both clinical evidence and medical expertise to enhance clinical judgment and decision-making.

Indexed as

CGRP-based therapyConsensus recommendationsGepantsMigraineUnited Arab Emirates (UAE)

Identifiers

PMID37792218
PMCPMC10630270
OpenAlexW4387326710

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.