Evidence map›Paper›PMID 37792044›Full record

ArticleArchives of toxicology2023

Species-differences in the in vitro biotransformation of trifluoroethene (HFO-1123).

R Dekant, R Bertermann, J Serban, S Sharma, M Shinohara, Y Morizawa, H Okamoto, W Brock, W Dekant, A Mally

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

R DekantDepartment of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
R BertermannDepartment of Inorganic Chemistry, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
J SerbanDepartment of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
S SharmaDepartment of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
M ShinoharaChemicals Company, AGC Inc, CSR Office, 1-5-1, Marunouchi, Chiyoda-ku, Tokyo, 100-8405, Japan.
Y MorizawaChemicals Company, AGC Inc, CSR Office, 1-5-1, Marunouchi, Chiyoda-ku, Tokyo, 100-8405, Japan.
H OkamotoChemicals Company, AGC Inc, CSR Office, 1-5-1, Marunouchi, Chiyoda-ku, Tokyo, 100-8405, Japan.
W BrockBrook Scientific Consulting LLC, Hilton Head Island, SC, USA.
W DekantDepartment of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany.
A MallyDepartment of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078, Würzburg, Germany. mally@toxi.uni-wuerzburg.de.ORCID http://orcid.org/0000-0002-5013-5080
University of Würzburg · DEGC Corporation (Japan) · JPScientific Consulting Group · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

1,1,2-Trifluoroethene (HFO-1123) is anticipated for use as a refrigerant with low global warming potential. Inhalation studies on HFO-1123 in rats indicated a low potential for toxicity (NOAELs ≥ 20,000 ppm). In contrast, single inhalation exposure of Goettingen

Indexed as

AcetylcysteineLyasesAnimalsBiotransformationGlutathioneHumansHydrocarbons, FluorinatedKidneyMiceRabbitsRatsSwineSwine, MiniatureAcetylcysteineGlutathioneHydrocarbons, FluorinatedLyasestrifluoroethene19F-NMRHFO-1123In vitro biotransformationLC–MS/MSMercapturic acid pathwayTrifluoroetheneβ-Lyase

Identifiers

PMID37792044
PMCPMC10567879
OpenAlexW4387326729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.