Evidence map›Paper›PMID 37791788›Full record

ArticlemSphere2023

Volatile profiling distinguishes

Amalia Z Berna, Joseph A Merriman, Leah Mellett, Danealle K Parchment, Michael G Caparon, Audrey R Odom John

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. AI-Powered Microscopic Diagnostic Techniques forJournal of dentistry (Shiraz, Iran) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Amalia Z BernaDepartment of Pediatrics, Washington University School of Medicine , St. Louis, Missouri, USA.ORCID 0000-0003-4932-5415
Joseph A MerrimanDepartment of Molecular Microbiology, Washington University School of Medicine , St. Louis, Missouri, USA.
Leah MellettDepartment of Molecular Microbiology, Washington University School of Medicine , St. Louis, Missouri, USA.
Danealle K ParchmentDepartment of Molecular Microbiology, Washington University School of Medicine , St. Louis, Missouri, USA.
Michael G CaparonDepartment of Molecular Microbiology, Washington University School of Medicine , St. Louis, Missouri, USA.
Audrey R Odom JohnDepartment of Pediatrics, Washington University School of Medicine , St. Louis, Missouri, USA.ORCID 0000-0001-8395-8537
Washington University in St. Louis · USChildren's Hospital of Philadelphia · US

Funding

TrainingP41GM103422 · NIGMS · WASHINGTON UNIVERSITY · PI YARASHESKI, KEVIN E · 2012 to 2019
$12.0M
MEP pathway resistance in Plasmodium falciparumR01AI103280 · NIAID · WASHINGTON UNIVERSITY · PI Audrey Ragan Odom John · 2013 to 2026
$5.5M
Breathprinting as a window into gut microbiome chemoecologyR01HD109963 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI Andrew Leon Kau, Audrey Ragan Odom John · 2022 to 2026
$3.4M
Inhibition of MEP pathway Isoprenoid BiosynthesisR01AI123433 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI DOWD, CYNTHIA SCHIECK, MEYERS, MARVIN J · 2016 to 2020
$2.6M
Towards noninvasive diagnosis of malariaR21AI144472 · NIAID · WASHINGTON UNIVERSITY · PI ODOM JOHN, AUDREY RAGAN · 2019 to 2020
$485k
Microbial Origin of Breath Volatile MetabolitesR21AI154370 · NIAID · WASHINGTON UNIVERSITY · PI KAU, ANDREW LEON, ODOM JOHN, AUDREY RAGAN · 2020 to 2021
$473k
SELECTIVE INHIBITION OF THE P. FALCIPARUM GLUCOSE TRANSPORTER PFHTR21AI130584 · NIAID · WASHINGTON UNIVERSITY · PI HRUZ, PAUL W · 2018 to 2019
$419k
NIAID NIH HHS AI103280NIAID NIH HHS R01 AI103280NIAID NIH HHS R01 AI123433NIAID NIH HHS R21 AI130584NIAID NIH HHS R21 AI144472NIAID NIH HHS R21 AI154370NICHD NIH HHS R01 HD109963NIGMS NIH HHS P41 GM103422NIGMS NIH HHS P41GM103422
6 · The paper itself

Abstract

Sore throat is one of the most common complaints encountered in the ambulatory clinical setting. Rapid, culture-independent diagnostic techniques that do not rely on pharyngeal swabs would be highly valuable as a point-of-care strategy to guide outpatient antibiotic treatment. Despite the promise of this approach, efforts to detect volatiles during oropharyngeal infection have yet been limited. In our research study, we sought to evaluate for specific bacterial volatile organic compounds (VOC) biomarkers in isolated cultures

Indexed as

PharyngitisStreptococcal InfectionsAnti-Bacterial AgentsBiomarkersChildHumansStreptococcus pyogenesAnti-Bacterial AgentsBiomarkersgroup A streptococcipharyngitisStreptococcus pyogenesvolatile organic compounds

Identifiers

PMID37791788
PMCPMC10597408
OpenAlexW4387326338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.