Evidence map›Paper›PMID 37791635›Full record

ArticleSoft matter2023

Surface tension measurement and calculation of model biomolecular condensates.

Jack Holland, Alfonso A Castrejón-Pita, Remco Tuinier, Dirk G A L Aarts, Timothy J Nott

Open access · hybridAbstract read
In one paragraph

Article in Soft matter, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  5. Review
  6. Nucleation Kinetics Reveals a Distinct Biological Function Space of Biomolecular Condensates.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jack HollandDepartment of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, Oxford, OX1 3QZ, UK. dirk.aarts@chem.ox.ac.uk.ORCID http://orcid.org/0000-0001-6086-9582
Alfonso A Castrejón-PitaDept. of Engineering Science, University of Oxford, Oxford, OX1 3PJ, UK.ORCID http://orcid.org/0000-0003-4995-2582
Remco TuinierLaboratory of Physical Chemistry, Department of Chemical Engineering and Chemistry & Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.ORCID http://orcid.org/0000-0002-4096-7107
Dirk G A L AartsDepartment of Chemistry, Physical and Theoretical Chemistry Laboratory, University of Oxford, Oxford, OX1 3QZ, UK. dirk.aarts@chem.ox.ac.uk.ORCID http://orcid.org/0000-0001-8333-015X
Timothy J NottDept. of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK. tim.nott@bioch.ox.ac.uk.ORCID http://orcid.org/0000-0002-5210-4931
University of Oxford · GBEindhoven University of Technology · NL

Funding

Wellcome Trust 202320/Z/16/Z
6 · The paper itself

Abstract

The surface tension of liquid-like protein-rich biomolecular condensates is an emerging physical principle governing the mesoscopic interior organisation of biological cells. In this study, we present a method to evaluate the surface tension of model biomolecular condensates, through straighforward sessile drop measurements of capillary lengths and condensate densities. Our approach bypasses the need for characterizing condensate viscosities, which was required in previously reported techniques. We demonstrate this method using model condensates comprising two mutants of the intrinsically disordered protein Ddx4

Indexed as

Biomolecular CondensatesVeinsSurface TensionViscosity

Identifiers

PMID37791635
PMCPMC10663989
OpenAlexW4386888215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.