Evidence map›Paper›PMID 37790888›Full record

ArticleJornal vascular brasileiro2023

Association between platelet lymphocyte ratio and neutrophil lymphocyte ratio and clinical outcomes following carotid endarterectomy.

Vinicius Adorno Gonçalves, Martin Andreas Geiger, Danilo Augusto Sarti, Ana Terezinha Guillaumon

Abstract read
In one paragraph

Article in Jornal vascular brasileiro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vinicius Adorno GonçalvesUniversidade Estadual de Campinas - UNICAMP, Faculdade de Ciências Médicas, Hospital de Clínicas, Campinas, SP, Brasil.ORCID 0000-0003-2086-1337
Martin Andreas GeigerUniversidade Estadual de Campinas - UNICAMP, Faculdade de Ciências Médicas, Hospital de Clínicas, Campinas, SP, Brasil.ORCID 0000-0001-7773-5580
Danilo Augusto SartiNational University of Ireland, Hamilton Institute, Maynooth, Ireland.
Ana Terezinha GuillaumonUniversidade Estadual de Campinas - UNICAMP, Faculdade de Ciências Médicas, Hospital de Clínicas, Campinas, SP, Brasil.ORCID 0000-0002-5487-4892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Approximately 30% of stroke cases result from carotid disease. Although several risk factors for complications after carotid endarterectomy have been identified, the existence of a biomarker that can estimate postoperative risk in these patients has not yet been proven. Objectives: This study aimed to investigate correlations between the platelet-lymphocyte ratio (PLR) and the neutrophil-lymphocyte ratio (NLR) and postoperative clinical outcomes in patients undergoing carotid endarterectomy. Methods: A retrospective study was conducted, including 374 patients who underwent carotid endarterectomy between 2002 and 2019 due to moderate to high extracranial internal carotid artery stenosis. Their platelet-lymphocyte ratio and neutrophil-lymphocyte ratios were obtained from the same blood samples. Results: There was a statistically significant correlation between the PLR and the occurrence of restenosis (p < 0.01) and acute myocardial infarction (AMI) after endarterectomy (p = 0.03). Additionally, there was a statistically significant correlation between the PLR and the combined outcomes stroke and/or AMI and/or death (p = 0.03) and stroke and/or AMI and/or death and/or restenosis (p < 0.01). However, there were no significant correlations between NLR and these outcomes (p = 0.05, p = 0.16). Conclusions: The platelet-lymphocyte ratio proved to be a useful test for predicting occurrence of strokes, acute myocardial infarctions, and deaths during the postoperative period after carotid endarterectomy. It was also associated with the risk of postoperative restenosis.

Indexed as

atherosclerosiscarotid endarterectomycarotid stenosismortalityplatelet count

Identifiers

PMID37790888
PMCPMC10545233

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.