Evidence map›Paper›PMID 37790732›Full record

ArticleBiofilm2023

Spectrum of activity of

Aliyah N Bennett, Katherine J Woolard, Amy Sorge, Christian Melander, John S Gunn

Open access · goldAbstract read
In one paragraph

Article in Biofilm, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aliyah N BennettCenter for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Katherine J WoolardDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, USA.
Amy SorgeDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, USA.
Christian MelanderDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, USA.
John S GunnCenter for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
University of Notre Dame · USNationwide Children's Hospital · US

Funding

Mechanisms of the Development and Maintenance of Salmonella Gallbladder CarriageR01AI116917 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI GUNN, JOHN S, MELANDER, CHRISTIAN COREY · 2015 to 2025
$6.1M
NIAID NIH HHS R01 AI116917
6 · The paper itself

Abstract

The ESKAPE pathogens are a group of bacteria that are a leading cause of health-care associated infections and are known to be agents of chronic, biofilm-mediated infections. These chronic bacterial infections often respond poorly to antibiotics and in some cases may require surgical intervention in order to cure the infection. As biofilms are often the critical mediator of a chronic infection, it is essential to develop therapies that target bacteria within the biofilm state. Herein, we report the development of a rapid, 96-well plate-based assay that employs conditions specific for each species to optimize biofilm production and allow for easy identification of differences in biofilm mass after treatment with anti-biofilm candidates. We used these ESKAPE-specific biofilm assays to test our previously identified

Indexed as

Antibiofilm small molecule compoundsAntibioticBiofilmESKAPE pathogens

Identifiers

PMID37790732
PMCPMC10542598
OpenAlexW4386947355

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.