Evidence map›Paper›PMID 37790584›Full record

ArticleClinical and translational radiation oncology2023

The need for consensus on delineation and dose constraints of dentofacial structures in paediatric radiotherapy: Outcomes of a SIOP Europe survey.

Angela Davey, Shermaine Pan, Abigail Bryce-Atkinson, Henry Mandeville, Geert O Janssens, Sarah M Kelly, Marinka Hol, Vivian Tang, Lucy Siew Chen Davies, Siop-Europe Radiation Oncology Working Group and 1 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 66% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Angela DaveyDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Shermaine PanDepartment of Proton Therapy, The Christie NHS Foundation Trust, Manchester, UK.
Abigail Bryce-AtkinsonDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
Henry MandevilleThe Royal Marsden NHS Foundation Trust, London, UK.
Geert O JanssensPrincess Maxima Center for Paediatric Oncology, Utrecht, The Netherlands.
Sarah M KellyEuropean Society for Paediatric Oncology (SIOP Europe), Clos Chapelle-aux-Champs 30, Brussels, Belgium.
Marinka HolPrincess Maxima Center for Paediatric Oncology, Utrecht, The Netherlands.
Vivian TangPaediatric Radiology, Royal Manchester Children's Hospital, Manchester, UK.
Lucy Siew Chen DaviesDepartment of Radiotherapy, The Christie NHS Foundation Trust, Manchester, UK.
Siop-Europe Radiation Oncology Working GroupEuropean Society for Paediatric Oncology (SIOP Europe), Clos Chapelle-aux-Champs 30, Brussels, Belgium.
Marianne AznarDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
University of Manchester · GBThe Christie NHS Foundation Trust · GBUniversity Medical Center Utrecht · NLEuropean Society for Paediatric Oncology · BEGhent University · BERoyal Manchester Children's Hospital · GBRoyal Marsden NHS Foundation Trust · GB

Funding

Cancer Research UK 28701
6 · The paper itself

Abstract

Background and purpose: Children receiving radiotherapy for head-and-neck tumours often experience severe dentofacial side effects. Despite this, recommendations for contouring and dose constraints to dentofacial structures are lacking in clinical practice. We report on a survey aiming to understand current practice in contouring and dose assessment to dentofacial structures. Methods: A digital survey was distributed to European Society for Paediatric Oncology members of the Radiation Oncology Working Group, and member-affiliated centres in Europe, Australia, and New Zealand. The questions focused on clinical practice and aimed to establish areas for future development. Results: Results from 52 paediatric radiotherapy centres across 27 countries are reported. Only 29/52 centres routinely delineated some dentofacial structures, with the most common being the mandible (25 centres), temporo-mandibular joint (22), dentition (13), orbit (10) and maxillary bone (eight). For most bones contoured, an Conclusion: Routine delineation of dentofacial structures is infrequent in paediatric radiotherapy. Based on survey findings, we aim to 1) define a consensus-contouring atlas for dentofacial structures, 2) develop auto-contouring solutions for dentofacial structures to aid clinical implementation, and 3) carry out treatment planning studies to investigate the importance of delineation of these structures for planning optimisation.

Indexed as

ContouringDentofacialDose-volume constraintsLate adverse effectsPaediatricsRadiotherapy

Identifiers

PMID37790584
PMCPMC10543782
OpenAlexW4386997427

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.