Evidence map›Paper›PMID 37790566›Full record

ArticlebioRxiv : the preprint server for biology2023

Mobile barrier mechanisms for Na

Parameswaran Hariharan, Yuqi Shi, Satoshi Katsube, Katleen Willibal, Nathan D Burrows, Patrick Mitchell, Amirhossein Bakhtiiari, Samantha Stanfield, Els Pardon, H Ronald Kaback and 4 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Parameswaran HariharanDepartment of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, School of Medicine, Lubbock, TX 79424, USA.
Yuqi ShiThermo Fisher Scientific, San Jose, CA 95134, USA.
Satoshi KatsubeDepartment of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, School of Medicine, Lubbock, TX 79424, USA.
Katleen WillibalVIB-VUB Center for Structural Biology, 1050 Brussel, Belgium.
Nathan D BurrowsDivision of CryoEM and Bioimaging, Stanford Synchrotron Radiation Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.
Patrick MitchellDivision of CryoEM and Bioimaging, Stanford Synchrotron Radiation Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.
Amirhossein BakhtiiariDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.
Samantha StanfieldDepartment of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, School of Medicine, Lubbock, TX 79424, USA.
Els PardonVIB-VUB Center for Structural Biology, 1050 Brussel, Belgium.
H Ronald KabackDepartment of Physiology, University of California, Los Angeles, Los Angeles, CA, USA.
Ruibin LiangDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.
Jan SteyaertVIB-VUB Center for Structural Biology, 1050 Brussel, Belgium.
Rosa VinerThermo Fisher Scientific, San Jose, CA 95134, USA.
Lan GuanDepartment of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, School of Medicine, Lubbock, TX 79424, USA.ORCID 0000-0002-2274-361X
Texas Tech University · USVIB-VUB Center for Structural Biology · BESLAC National Accelerator Laboratory · USThermo Fisher Scientific (United States) · USUniversity of California, Los Angeles · US

Funding

The Stanford-SLAC CryoEM Center supplementU24GM129541 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH, HEDMAN, BRITT · 2018 to 2023
$54.8M
Integrated approaches to symport mechanisms of membrane transportersR01GM122759 · NIGMS · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI GUAN, LAN · 2018 to 2021
$1.4M
NIGMS NIH HHS R01 GM122759NIGMS NIH HHS U24 GM129541
6 · The paper itself

Abstract

While many 3D structures of cation-coupled transporters have been determined, the mechanistic details governing the obligatory coupling and functional regulations still remain elusive. The bacterial melibiose transporter (MelB) is a prototype of the Na

Identifiers

PMID37790566
PMCPMC10542114
OpenAlexW4386862288

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.