Evidence map›Paper›PMID 37790552›Full record

ArticleResearch square2023

Cross-species epigenetic regulation of nucleus accumbens KCNN3 transcripts by excessive ethanol drinking.

Rita Cervera Juanes, Patrick Mulholland, Audrey Padula, Larry Wilhelm, Byung Park, Kathleen Grant, Betsy Ferguson

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rita Cervera JuanesAtrium Health Wake Forest Baptist.
Patrick MulhollandMUSC.ORCID 0000-0003-0780-5971
Audrey Padula
Larry Wilhelm
Byung Park
Kathleen GrantOregon Health & Science University.ORCID 0000-0002-0380-7219
Betsy FergusonOregon Health & Sciences University/Oregon National Primate Research Center.ORCID 0000-0002-6992-3538
Oregon National Primate Research Center · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
TREATING ETHANOL WITHDRAWAL WITH LORAZEPAM/NALTREXONEP50AA010761 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Patrick J. Mulholland · 1996 to 2026
$46.8M
Stress and Ethanol Self-Administration in MonkeysU01AA013510 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KATHLEEN A GRANT · 2002 to 2026
$11.8M
Monkey Alcohol Tissue Research Resource (MATRR)R24AA019431 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Mary Lauren Benton, Verginia Carmella Cuzon Carlson · 2010 to 2026
$10.3M
INIA: Stress, Anxiety of Alcohol AbuseU01AA013641 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI GRANT, KATHLEEN A · 2002 to 2015
$8.8M
INIA: Stress, Anxiety and Excessive Alcohol Drinking (Administrative Core)U24AA013641 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KATHLEEN A GRANT · 2016 to 2026
$3.4M
Kv7 channels and heavy alcohol drinkingR01AA023288 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MULHOLLAND, PATRICK J. · 2014 to 2023
$3.4M
Distinguishing preexistent and induced epigenetic risk for alcohol use disordersR01AA026278 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CERVERA JUANES, RITA P · 2019 to 2023
$3.2M
Identifying new targets for the treatment of alcohol dependence and relapse: epigenetic analysis of the abstinent brainR01AA027552 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CERVERA JUANES, RITA P · 2020 to 2024
$2.6M
Stress and Ethanol Dependence: SK Channels and GlutamateU01AA020930 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MULHOLLAND, PATRICK J. · 2012 to 2021
$2.6M
Genetic and Epigenetic Analysis of Alcohol Self-Administration in MonkeysU01AA020928 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI FERGUSON, BETSY M · 2012 to 2016
$1.3M
Alcohol-associated DNA Methylation in the Primate BrainR03AA026092 · NIAAA · OREGON HEALTH & SCIENCE UNIVERSITY · PI CERVERA JUANES, RITA P · 2018 to 2019
$175k
NIAAA NIH HHS P50 AA010761NIAAA NIH HHS R01 AA023288NIAAA NIH HHS R01 AA026278NIAAA NIH HHS R01 AA027552NIAAA NIH HHS R03 AA026092NIAAA NIH HHS R24 AA019431NIAAA NIH HHS U01 AA013510NIAAA NIH HHS U01 AA013641NIAAA NIH HHS U01 AA020928NIAAA NIH HHS U01 AA020930NIAAA NIH HHS U24 AA013641NIH HHS P51 OD011092
6 · The paper itself

Abstract

The underlying genetic and epigenetic mechanisms driving functional adaptations in neuronal excitability and excessive alcohol intake are poorly understood. Small-conductance Ca

Identifiers

PMID37790552
PMCPMC10543433
OpenAlexW4386766638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.