Evidence map›Paper›PMID 37790548›Full record

ArticlebioRxiv : the preprint server for biology2023

Impaired bone morphogenetic protein signaling pathways disrupt decidualization in endometriosis.

Zian Liao, Suni Tang, Peixin Jiang, Ting Geng, Dominique I Cope, Timothy N Dunn, Joie Guner, Linda Alpuing Radilla, Xiaoming Guan, Diana Monsivais

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Zian LiaoDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, 77030, USA.
Suni TangDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, 77030, USA.
Peixin JiangDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, 77030, USA.
Ting GengDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, 77030, USA.
Dominique I CopeDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, 77030, USA.
Timothy N DunnDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, 77030, USA.
Joie GunerDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of Southern California, Los Angeles, CA, 90033, USA.
Linda Alpuing RadillaDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, 77030, USA.
Xiaoming GuanDepartment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, 77030, USA.
Diana MonsivaisDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, TX, 77030, USA.ORCID 0000-0001-5660-6392
Baylor College of Medicine · USThe University of Texas MD Anderson Cancer Center · USUniversity of Southern California · US

Funding

Transforming growth factor β family signaling pathways in ovarian and uterine biologyR01HD032067 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MARTIN M. MATZUK · 1994 to 2026
$9.9M
Kinases as Therapeutic Targets for EndometriosisR01HD110038 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MARTIN M. MATZUK · 2022 to 2026
$3.4M
Targeting the endometrial stem cell niche inendometriosisR01HD105800 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Diana Monsivais · 2022 to 2026
$2.5M
The role of SMAD1 and SMAD5 in hormonal response, endometrial receptivity and glandular functionR00HD096057 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MONSIVAIS, DIANA · 2020 to 2022
$728k
NICHD NIH HHS R00 HD096057NICHD NIH HHS R01 HD032067NICHD NIH HHS R01 HD105800NICHD NIH HHS R01 HD110038
6 · The paper itself

Abstract

It is hypothesized that impaired endometrial decidualization contributes to decreased fertility in individuals with endometriosis. To identify the molecular defects that underpin defective decidualization in endometriosis, we subjected endometrial stromal cells from individuals with or without endometriosis to time course

Indexed as

Bone morphogenetic proteinsdecidualizationendometriosisinfertilityorganoids

Identifiers

PMID37790548
PMCPMC10542516
OpenAlexW4386982075

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.