Evidence map›Paper›PMID 37790530›Full record

ArticlebioRxiv : the preprint server for biology2024

Natural variation of immune epitopes reveals intrabacterial antagonism.

Danielle M Stevens, Alba Moreno-Pérez, Alexandra J Weisberg, Charis Ramsing, Judith Fliegmann, Ning Zhang, Melanie Madrigal, Gregory Martin, Adam Steinbrenner, Georg Felix and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Danielle M StevensIntegrative Genetics and Genomics Graduate Group, University of California, Davis, Davis CA 95616, USA.ORCID 0000-0001-5630-137X
Alba Moreno-PérezDepartment of Plant Pathology, University of California, Davis, Davis CA 95616, USA.ORCID 0000-0001-5089-8654
Alexandra J WeisbergDepartment of Botany and Plant Pathology, Oregon State University, Corvallis OR, USA.ORCID 0000-0002-0045-1368
Charis RamsingDepartment of Plant Pathology, University of California, Davis, Davis CA 95616, USA.ORCID 0000-0002-3932-1384
Judith FliegmannCenter for Plant Molecular Biology (ZMBP), University of Tübingen, 72074 Tübingen, Germany.ORCID 0000-0003-1021-8006
Ning ZhangBoyce Thompson Institute for Plant Research, Ithaca NY, USA.ORCID 0000-0003-2775-1755
Melanie MadrigalDepartment of Plant Pathology, University of California, Davis, Davis CA 95616, USA.
Gregory MartinBoyce Thompson Institute for Plant Research, Ithaca NY, USA.ORCID 0000-0003-0044-6830
Adam SteinbrennerUniversity of Washington, Department of Biology, Box 351800, Seattle, WA, 98195, USA.ORCID 0000-0002-7493-678X
Georg FelixCenter for Plant Molecular Biology (ZMBP), University of Tübingen, 72074 Tübingen, Germany.ORCID 0000-0002-6746-6185
Gitta CoakerDepartment of Plant Pathology, University of California, Davis, Davis CA 95616, USA.ORCID 0000-0003-0899-2449
University of California, Davis · USCornell University · USUniversity of Tübingen · DEOregon State University · USUniversity of Washington · US

Funding

Immune Perception of Bacterial Pathogens in PlantsR35GM136402 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Gitta Laurel Coaker · 2020 to 2026
$3.0M
NIGMS NIH HHS R35 GM136402
6 · The paper itself

Abstract

Plants and animals detect biomolecules termed Microbe-Associated Molecular Patterns (MAMPs) and induce immunity. Agricultural production is severely impacted by pathogens which can be controlled by transferring immune receptors. However, most studies use a single MAMP epitope and the impact of diverse multi-copy MAMPs on immune induction is unknown. Here we characterized the epitope landscape from five proteinaceous MAMPs across 4,228 plant-associated bacterial genomes. Despite the diversity sampled, natural variation was constrained and experimentally testable. Immune perception in both

Indexed as

comparative genomicsintrabacterial antagonismmicrobe-associated molecular patternsnatural variationplant innate immunity

Identifiers

PMID37790530
PMCPMC10543004
OpenAlexW4386913172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.