Evidence map›Paper›PMID 37790468›Full record

ArticlebioRxiv : the preprint server for biology2023

Mineralocorticoid receptor-independent activation of ENaC in bile duct ligated mice.

Xue-Ping Wang, Stephanie M Mutchler, Rolando Carrisoza-Gáytan, Mohammad Al-Bataineh, Catherine J Baty, Amber Vandevender, Priyanka Srinivasan, Roderick J Tan, Michael J Jurczak, Lisa M Satlin and 1 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xue-Ping WangDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, Pennsylvania.
Stephanie M MutchlerDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, Pennsylvania.
Rolando Carrisoza-GáytanDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
Mohammad Al-BatainehDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, Pennsylvania.
Catherine J BatyDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, Pennsylvania.
Amber VandevenderDepartment of Medicine, Division of Endocrinology and Metabolism, University of Pittsburgh, Pittsburgh, Pennsylvania.
Priyanka SrinivasanDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, Pennsylvania.
Roderick J TanDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, Pennsylvania.
Michael J JurczakDepartment of Medicine, Division of Endocrinology and Metabolism, University of Pittsburgh, Pittsburgh, Pennsylvania.
Lisa M SatlinDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York.
Ossama B KashlanDepartment of Medicine, Renal-Electrolyte Division, University of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh · USIcahn School of Medicine at Mount Sinai · US

Funding

Single Nephron and MetabolomicsP30DK079307 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2008 to 2022
$13.4M
Pittsburgh Liver Research CenterP30DK120531 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAVID A GELLER · 2019 to 2026
$10.9M
T32 Research Training in Diabetes and EndocrinologyT32DK007052 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROBERT M O'DOHERTY · 1986 to 2026
$6.3M
Resource Development CoreU54DK137329 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Thomas R Kleyman · 2023 to 2026
$4.8M
Renal and Epithelial Biology Training ProgramT32DK061296 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KLEYMAN, THOMAS R · 2002 to 2022
$3.1M
Effect of Renal Nerves on Chronic Kidney DiseaseR01DK131991 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Roderick Jason Tan · 2022 to 2026
$2.6M
ENaC regulation by biliary factorsR01DK125439 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KASHLAN, OSSAMA B · 2020 to 2023
$1.8M
The University of Pittsburgh Summer Research Internship Program kidney workshop (SRIP-Kid)R25DK119180 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JACQUELINE HO, Sunder Sims-Lucas · 2021 to 2026
$648k
Integrated perfusion and confocal imaging systemS10OD021627 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WEISZ, ORA A · 2016 to 2016
$479k
Role of the MUC1/HIF-1a Complex in the kidney proximal tubule during ischemia-reperfusion injury.R03DK131093 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AL-BATAINEH, MOHAMMAD · 2022 to 2023
$236k
BLRD VA I01 BX005680NIDDK NIH HHS P30 DK079307NIDDK NIH HHS P30 DK120531NIDDK NIH HHS R01 DK125439NIDDK NIH HHS R01 DK131991NIDDK NIH HHS R03 DK131093NIDDK NIH HHS R25 DK119180NIDDK NIH HHS T32 DK007052NIDDK NIH HHS T32 DK061296NIDDK NIH HHS U54 DK137329NIH HHS S10 OD021627
6 · The paper itself

Abstract

Sodium and fluid retention in liver disease is classically thought to result from reduced effective circulating volume and stimulation of the renin-angiotensin-aldosterone system (RAAS). Aldosterone dives Na

Indexed as

bile acidsfluid retentionliver-kidney axissodium avidity

Identifiers

PMID37790468
PMCPMC10542149
OpenAlexW4386949255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.