Evidence map›Paper›PMID 37790452›Full record

ArticleResearch square2023

MTGR1 is required to maintain small intestinal stem cell populations.

Christopher Williams, Rachel Brown, Yue Zhao, Jing Wang, Zhengyi Chen, Koral Blunt, Jennifer Pilat, Bobak Parang, Yash Choksi, Ken Lau and 6 more

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Christopher WilliamsVanderbilt University Medical Center.
Rachel BrownVanderbilt University.
Yue ZhaoVanderbilt University.
Jing WangVanderbilt University Medical Center.
Zhengyi ChenVanderbilt University.ORCID 0000-0003-4774-945X
Koral BluntVanderbilt University.
Jennifer PilatVanderbilt University.ORCID 0000-0001-5385-3232
Bobak ParangVanderbilt University.
Yash ChoksiVanderbilt University Medical Center.
Ken LauVanderbilt University.ORCID 0000-0001-8438-0319
Scott HiebertVanderbilt University.
Sarah ShortUniversity of Iowa.
Justin JacobseVanderbilt.ORCID 0000-0002-1899-0319
Yanwen XuVanderbilt.
Yilin YangVanderbilt.ORCID 0009-0000-9869-4044
Jeremy GoettelVanderbilt.
Vanderbilt University Medical Center · USVanderbilt University · USLeiden University Medical Center · NLThe Ohio State University · USUniversity of Iowa · USVA Tennessee Valley Healthcare System · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3M
Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
Tuft cell heterogeneity in function, lineage, and structure in ileal inflammatory diseaseR01DK103831 · NIDDK · VANDERBILT UNIVERSITY · PI LAU, KEN S · 2016 to 2024
$4.4M
Role of PRC1 in RUNX1-ETO-mediated transcriptional controlR01CA255446 · NCI · VANDERBILT UNIVERSITY · PI HODGES, EMILY · 2021 to 2025
$2.1M
Selenium in gastrointestinal inflammatory diseasesR01DK099204 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILLIAMS, CHRISTOPHER S. · 2014 to 2018
$1.8M
Antioxidant regulation of intestinal homeostasis and diseaseK01DK123495 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHORT, SARAH PALMER · 2020 to 2024
$732k
Mechanisms of Transcriptional Regulation by MTG16 in the IntestineF30DK120149 · NIDDK · VANDERBILT UNIVERSITY · PI BROWN, RACHEL ELIZABETH · 2018 to 2021
$146k
The Role of BVES in Intestinal Repair Programs and Inflammatory Bowel DiseaseF30DK096718 · NIDDK · VANDERBILT UNIVERSITY · PI PARANG, BOBAK · 2012 to 2015
$106k
Defining the role of intestinal epithelial selenoprotein P (SEPP1) in sporadic colorectal carcinogenesisF31CA232272 · NCI · VANDERBILT UNIVERSITY · PI PILAT, JENNIFER MARIE · 2019 to 2021
$90k
BLRD VA I01 BX001426NCI NIH HHS F31 CA232272NCI NIH HHS P30 CA068485NCI NIH HHS R01 CA255446NEI NIH HHS P30 EY008126NIDDK NIH HHS F30 DK096718NIDDK NIH HHS F30 DK120149NIDDK NIH HHS K01 DK123495NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK099204NIDDK NIH HHS R01 DK103831NIDDK NIH HHS U24 DK059637
6 · The paper itself

Abstract

Undifferentiated intestinal stem cells (ISCs), particularly those marked by

Identifiers

PMID37790452
PMCPMC10543309
OpenAlexW4386924259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.