ArticleToxicology reports2023
Case report: Management of an unknown TCA diagnosis: The importance of rapid diagnosis and the use of CVVHDF in toxin elimination.
Article in Toxicology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Survival after multiple in-hospital cardiac arrests due to severe amitriptyline poisoning- a case report.International journal of emergency medicine · 2026Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This case report highlights the effective medical management of a 27-year-old woman in critical condition due to an unknown medication overdose. The patient's initial condition at the emergency department (ED) indicated TCA (Tricyclic antidepressant) toxicity, which implied a poor prognosis based on clinical presentation and measurable criteria. The patient's systemic collapse was managed emergently in accordance with the TOXBASE guidelines. Additional supportive measures, including Continuous Venovenous Hemodiafiltration (CVVHDF), were employed in this severe case. Swift therapeutic interventions administered in the Emergency Department (ED) and Intensive Care Unit (ICU) resulted in enhanced clinical outcomes and improved haemodynamic status within five days. The patient successfully achieved complete clinical recovery without any neurological sequelae. She was discharged home within a week. This case underscores the importance of early recognition and highlights the utilisation of CVVHDF as an adjunct therapy in the advent of a lethal TCA overdose.
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