Evidence map›Paper›PMID 37789876›Full record

ArticleInfluenza and other respiratory viruses2023

Two-year trajectories of COVID-19 symptoms and their association with illness perception: A prospective cohort study in Amsterdam, the Netherlands.

Elke Wynberg, Anouk Verveen, Hugo D G van Willigen, Pythia Nieuwkerk, Udi Davidovich, Anja Lok, Menno D de Jong, Godelieve J de Bree, Tjalling Leenstra, Hans Knoop and 3 more

Abstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Elke WynbergDepartment of Infectious Diseases Public Health Service of Amsterdam Amsterdam the Netherlands.ORCID 0000-0002-8245-086X
Anouk VerveenDepartment of Medical Psychology, Amsterdam UMC, Amsterdam Public Health Research Institute University of Amsterdam Amsterdam the Netherlands.
Hugo D G van WilligenDepartment of Medical Microbiology & Infection Prevention, Amsterdam UMC University of Amsterdam, Amsterdam Institute for Infection and Immunity Amsterdam the Netherlands.
Pythia NieuwkerkDepartment of Medical Psychology, Amsterdam UMC, Amsterdam Public Health Research Institute University of Amsterdam Amsterdam the Netherlands.
Udi DavidovichDepartment of Infectious Diseases Public Health Service of Amsterdam Amsterdam the Netherlands.
Anja LokDepartment of Psychiatry, Amsterdam UMC University of Amsterdam Amsterdam the Netherlands.
Menno D de JongDepartment of Medical Microbiology & Infection Prevention, Amsterdam UMC University of Amsterdam, Amsterdam Institute for Infection and Immunity Amsterdam the Netherlands.
Godelieve J de BreeDepartment of Infectious Diseases, Amsterdam UMC, University of Amsterdam Amsterdam Institute for Infection and Immunity Amsterdam the Netherlands.
Tjalling LeenstraCenter for Infectious Disease Control (LCI) National Institute for Public Health and the Environment (RIVM) Bilthoven Netherlands.
Hans KnoopDepartment of Medical Psychology, Amsterdam UMC, Amsterdam Public Health Research Institute University of Amsterdam Amsterdam the Netherlands.
Maria PrinsDepartment of Infectious Diseases Public Health Service of Amsterdam Amsterdam the Netherlands.
Anders BoydDepartment of Infectious Diseases Public Health Service of Amsterdam Amsterdam the Netherlands.
RECoVERED Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We used data from a prospective cohort to explore 2-year trajectories of 'long COVID' (persistent symptoms after SARS-CoV-2 infection) and their association with illness perception. Methods: RECoVERED participants (adults; prospectively enrolled following laboratory-confirmed SARS-CoV-2 infection, May 2020-June 2021) completed symptom questionnaires at months 2-12, 18 and 24, and the Brief Illness Perception Questionnaire (B-IPQ) at months 1, 6 and 12. Using group-based trajectory models (GBTM), we modelled symptoms (mean total numbers and proportion with four specific complaints), including age, sex, BMI and timing of infection as covariates. In a multivariable linear mixed-effects model, we assessed the association between symptom trajectories and repeated B-IPQ scores. Results: Among 292 participants (42% female; median age 51 [IQR = 36-62]), four trajectories were identified, ranging from Trajectory 4 (8.9%; 6 + symptoms) to Trajectory 1 (24.8%; no symptoms). The occurrence of fatigue and myalgia increased among 23% and 12% of participants, respectively. Individuals in Trajectory 4 experienced more negative adjusted B-IPQ scores over time than those in Trajectories 1-3. Conclusions: We observed little fluctuation in the total number of symptoms, but individual symptoms may develop as others resolve. Reporting a greater number of symptoms was congruent with more negative illness perception over time.

Indexed as

COVID-19AdultFemaleHumansMaleMiddle AgedNetherlandsPerceptionProspective StudiesSARS-CoV-2Surveys and QuestionnairesCOVID‐19illness perceptionsequelaesymptomstrajectories

Identifiers

PMID37789876
PMCPMC10542619

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.