Evidence map›Paper›PMID 37789737›Full record

ArticlePaediatric anaesthesia2023

Opioid prescription rates associated with surgery among adolescents in the United States from 2015 to 2020.

Joseph T Sofia, Agnes Kim, Ian Jones, Jennifer A Rabbitts, Cornelius B Groenewald

Open access · hybridAbstract read
In one paragraph

Article in Paediatric anaesthesia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Pain severity and opioid use in patients with spine-related diagnoses.Frontiers in pain research (Lausanne, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Joseph T SofiaDepartment of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
Agnes KimMedical College of Georgia at Augusta University, Augusta University/University of Georgia Medical Partnership, Athens, Georgia, USA.
Ian JonesDepartment of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
Jennifer A RabbittsDepartment of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, Washington, USA.ORCID 0000-0003-4800-1080
Cornelius B GroenewaldDepartment of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, Washington, USA.ORCID 0000-0001-7601-0270
Seattle Children's Hospital · USUniversity of Washington · USUniversity of Georgia · US

Funding

Sleep Disturbances and Long-term Outcomes after Critical Illness in ChildrenK23HL138155 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI GROENEWALD, CORNELIUS BOTHA · 2018 to 2022
$839k
Preventing the Transition from Acute to Chronic Musculoskeletal Pain in Adolescents after Surgery: The Role of SleepK24AR080786 · NIAMS · STANFORD UNIVERSITY · PI Jennifer Rabbitts · 2023 to 2026
$712k
NHLBI NIH HHS K23 HL138155NIAMS NIH HHS K24 AR080786NIH HHS
6 · The paper itself

Abstract

introductionThe United States currently faces an epidemic of opioid misuse which extends to adolescent surgical populations. Opioid prescriptions after surgery are associated with persistent opioid use and serve as a reservoir for diversion. However, it is unclear what proportion of opioid prescriptions are surgical, and little is known about trends in opioid prescription rates associated with surgery in adolescents in the United States. This study aims to describe national trends in postsurgical opioid prescription rates over time among adolescents in the United States.

methodsWe conducted a population-based cross-sectional analysis of data captured in the Medical Expenditure Panel Survey (MEPS) from 2015 to 2020. MEPS classified adolescents 10-19 years of age (n = 26 909) as having a surgical procedure if they had any inpatient, outpatient, or emergency department visit during which a surgical procedure was performed.

resultsMean age (SD) of the sample was 14.4 (0.01) years. Sociodemographic characteristics were representative of the USA adolescent population. In total, 4.7% of adolescents underwent a surgical procedure. The surgery rate remained stable between 2015 (4.3%): and 2020 (4.4%) and was lower among minority populations. The combined rate of opioid prescribing for surgical and nonsurgical indications significantly decreased from 4.1% in 2015 to 1.4% in 2020 among all adolescents, an estimated difference of 2.7% (95% confidence interval (CI): 1.7%-3.7%, p < .0001). However, opioid prescribing for surgery remained relatively stable (1% in 2015 vs. 0.8% in 2020). DISCUSSION: Opioid prescription rates associated with surgery remained stable between 2015 and 2020 in the United States, despite significant decreases in prescribing among nonsurgical populations. Surgery is now a leading source of medical prescribed opioids among adolescents. Secondary findings included a stable trend in surgery utilization between 2015 and 2020, as well as continued racial disparities, both in terms of surgery utilization and opioid prescribing.

conclusionThe large number of adolescents being prescribed opioids for surgery in the USA each year, suggests there is a need for national guidelines aimed at adolescent opioid use, similar to the recent CDC guidelines aimed at adult opioid use.

Indexed as

Analgesics, OpioidOpioid-Related DisordersAdolescentAdultCross-Sectional StudiesDrug PrescriptionsHumansPractice Patterns, Physicians'PrescriptionsUnited StatesAnalgesics, Opioidadolescentsopioidsurgery

Identifiers

PMID37789737
PMCPMC10872763
OpenAlexW4387326380

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.