Evidence map›Paper›PMID 37789727›Full record

ArticlePsychiatric services (Washington, D.C.)2024

Trends in Attention-Deficit Hyperactivity Disorder Diagnosis and Pharmacotherapy Among Adults With Opioid Use Disorder.

Tae Woo Park, Tithi D Baul, Jake R Morgan, Timothy E Wilens, Amy M Yule

Open access · greenAbstract read
In one paragraph

Article in Psychiatric services (Washington, D.C.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tae Woo ParkDepartment of Psychiatry, University of Pittsburgh, Pittsburgh (Park); Department of Psychiatry, Boston Medical Center, and Boston University School of Medicine, Boston (Baul, Yule); Boston University School of Public Health, Boston (Morgan); Department of Psychiatry, Massachusetts General Hospital, and Harvard Medical School, Boston (Wilens).
Tithi D BaulDepartment of Psychiatry, University of Pittsburgh, Pittsburgh (Park); Department of Psychiatry, Boston Medical Center, and Boston University School of Medicine, Boston (Baul, Yule); Boston University School of Public Health, Boston (Morgan); Department of Psychiatry, Massachusetts General Hospital, and Harvard Medical School, Boston (Wilens).
Jake R MorganDepartment of Psychiatry, University of Pittsburgh, Pittsburgh (Park); Department of Psychiatry, Boston Medical Center, and Boston University School of Medicine, Boston (Baul, Yule); Boston University School of Public Health, Boston (Morgan); Department of Psychiatry, Massachusetts General Hospital, and Harvard Medical School, Boston (Wilens).
Timothy E WilensDepartment of Psychiatry, University of Pittsburgh, Pittsburgh (Park); Department of Psychiatry, Boston Medical Center, and Boston University School of Medicine, Boston (Baul, Yule); Boston University School of Public Health, Boston (Morgan); Department of Psychiatry, Massachusetts General Hospital, and Harvard Medical School, Boston (Wilens).
Amy M YuleDepartment of Psychiatry, University of Pittsburgh, Pittsburgh (Park); Department of Psychiatry, Boston Medical Center, and Boston University School of Medicine, Boston (Baul, Yule); Boston University School of Public Health, Boston (Morgan); Department of Psychiatry, Massachusetts General Hospital, and Harvard Medical School, Boston (Wilens).
Boston University · US

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Bruce R Schackman · 2015 to 2026
$20.7M
Does Treating Young Persons Psychopathology Prevent the Onset of Opioid and other Substance Use Disorders?UH3DA050252 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI WILENS, TIMOTHY E, YULE, AMY · 2020 to 2020
$3.0M
Distress Tolerance and Benzodiazepine Discontinuation in Opioid Agonist TherapyK23DA044321 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PARK, TAE WOO · 2017 to 2021
$927k
NCATS NIH HHS UL1 TR001430NIDA NIH HHS K23 DA044321NIDA NIH HHS P30 DA040500NIDA NIH HHS UH3 DA050252
6 · The paper itself

Abstract

objectiveThis study aimed to assess nationwide trends in attention-deficit hyperactivity disorder (ADHD) diagnoses and pharmacotherapy among patients with opioid use disorder and ADHD and to examine factors predicting receipt of stimulant medications among patients receiving medications for opioid use disorder (MOUDs).

methodsA claims-based database of commercially insured patients ages 13-64 was used to conduct two analyses: an annual cross-sectional study of 387,980 patients diagnosed as having opioid use disorder (2007-2017) to estimate the prevalence of ADHD diagnoses and pharmacotherapy, and a retrospective cohort study of 158,591 patients receiving MOUDs to test, with multivariable regression, the association between patient characteristics and receipt of stimulant medication.

resultsFrom 2007 to 2017, the prevalence of ADHD diagnoses increased from 4.6% to 15.1% and the rate of ADHD pharmacotherapy increased from 42.6% to 51.8% among patients with opioid use disorder. Among all patients receiving MOUDs, 10.5% received at least one prescription stimulant during the study period. Female sex; residence in the southern United States; and ADHD, mood, and anxiety disorder diagnoses were associated with increased likelihood of stimulant receipt. Stimulant use disorder and other substance use disorder diagnoses were associated with decreased likelihood of stimulant receipt.

conclusionsADHD diagnoses and pharmacotherapy among patients with opioid use disorder have increased. A minority of patients with ADHD and taking MOUDs received a stimulant. Further study is needed of the benefits and risks of ADHD pharmacotherapy for patients with opioid use disorder.

Indexed as

Attention Deficit Disorder with HyperactivityCentral Nervous System StimulantsOpioid-Related DisordersAdultCross-Sectional StudiesFemaleHumansRetrospective StudiesUnited StatesCentral Nervous System StimulantsAmphetaminesAttention-deficit disordersOpioid use disorderSubstance use

Identifiers

PMID37789727
PMCPMC11175591
OpenAlexW4387326647

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.