SynthesisAsia Pacific journal of clinical nutrition2023
Premorbid sarcopenia and functional outcome after acute stroke: a meta-analysis.
Synthesis in Asia Pacific journal of clinical nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.
- Association of Sarcopenia With Global, Motor, Cognitive, and Swallowing Function Prognosis in Stroke Patients: A Systematic Review and Meta-Analysis.Brain and behavior · 2026Pooled it
- Association between temporalis muscle thickness and functional outcomes in acute stroke: A meta-analysis and GRADE approach.The journal of nutrition, health & aging · 2025Pooled it
- Improvements in Gait Function Following Integrative Korean-Western Medicine Treatment in Older Adults with Chronic Stroke: A Retrospective Exploratory Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Impact of Sarcopenia on outcomes of pulmonary embolism: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2026Review
- Construction and Validation of a Risk Prediction Model Incorporating Temporal Muscle Thickness for Adverse Outcome in Acute Ischemic Stroke Patients.Journal of central nervous system disease · 2026Article
- Nutritional risk, cold exposure, and stroke severity in older adults: an exploratory analysis of the "collapsed furnace" hypothesis.Frontiers in public health · 2026Article
- The Association Between Possible Sarcopenia and Delirium Onset in Older Patients With Acute Stroke.Cureus · 2025Article
- Sex differences in sarcopenia prevalence and muscle-related outcomes among post-stroke inpatients.European geriatric medicine · 2025Article
- Article
- Pectoralis major muscle index as an opportunistic predictor of mortality in acute stroke patients treated with intravenous thrombolysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Causal association of sarcopenia-related traits with brain cortical structure: a bidirectional Mendelian randomization study.Aging clinical and experimental research · 2025Article
- Mechanisms of how sarcopenia affects functional outcomes in acute ischaemic stroke.Brain communications · 2025Article
- Effect of Sarcopenia on Functional Recovery in Acute Stroke Patients Admitted for Standard Rehabilitation Program.Medicina (Kaunas, Lithuania) · 2024Article
- Effects of muscle strength exercise on muscle mass and muscle strength in patients with stroke: a systematic review and meta-analysis.Journal of exercise rehabilitation · 2024Article
- Vascular Impairment, Muscle Atrophy, and Cognitive Decline: Critical Age-Related Conditions.Biomedicines · 2024Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesSarcopenia is prevalent in patients with stroke. However, the relationship between sarcopenia and poor functional outcome of patients with acute stroke remains unknown. A systematic review and meta-analysis was performed to evaluate the above association. METHODS AND STUDY
designObservational studies which evaluated the influence of sarcopenia on functional outcome in patients with acute stroke were retrieved by search the PubMed, Embase, Cochrane Library, and Web of Science databases. A poor functional outcome was defined as modified Rankin scale (mRS) of two or more points during follow-up. Two authors independently collected the data of study characteristics and outcomes. A random-effects model was used to pool the results via incorporating the influence of possible between-study heterogeneity.
resultsNine datasets from seven cohort studies contributed to the meta-analysis. A total of 1774 patients with stroke were included, and 481 (27.1%) of them had sarcopenia. Compared to patients without sarcopenia, those with sarcopenia were associated with a higher risk of poor functional outcome during follow-up duration up to 6 months after stroke onset (odds ratio: 2.42, 95% confidence interval: 1.76 to 3.33, p < 0.001) with mild heterogeneity (I2 = 23%). Subgroup analyses according to study design (prospective versus retrospective), sex of the patient, type of stroke (ischemic or mixed), diagnostic methods for sarcopenia, follow-up duration and cutoff scores for mRS showed consistent results (p for subgroup analyses all > 0.05).
conclusionsSarcopenia may be associated with poor functional outcome in patients with acute stroke.
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Registered trials
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