SynthesisBMC surgery2023
Plus Sutures for preventing surgical site infection: a systematic review of clinical outcomes with economic and environmental models.
Synthesis in BMC surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review and meta-analysis of outcomes associated with incisional and organ/space surgical site infections in abdominal surgery patients.Antimicrobial resistance and infection control · 2025Pooled it
- Systematic review and meta-analysis comparing surgical site infection in abdominal surgery between triclosan-coated and uncoated sutures.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- MonocrylMedical sciences (Basel, Switzerland) · 2026Article
- Multimodal assessment of the prevention of surgical site infections in breast surgery in a French university hospital.Antimicrobial resistance and infection control · 2025Observational
- Modeled Carbon Footprint of Change of Sterile Gloves and Instruments for Abdominal Wound Closure.JAMA network open · 2025Article
- Assessing the environmental impact associated with disruptive surgical bleeding.Surgery open science · 2025Article
- Economic analysis of triclosan-coated versus uncoated sutures at preventing surgical site infection in patients undergoing abdominal surgery.BMJ surgery, interventions, & health technologies · 2025Article
- Article
- RETRACTED: Effect of intra-wound vancomycin on the surgical site wound infection after spinal surgery: A meta-analysis.International wound journal · 2024Review
- Optimizing Surgical Site Infection Prevention in Dermatologic Surgery.Journal of cutaneous medicine and surgeryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgical site infections (SSIs) represent ~ 20% of all hospital-acquired infections in surgical patients and are associated with prolonged hospital stay, admission to intensive care, and mortality. We conducted a systematic review with economic and environmental models to assess whether triclosan-coated sutures (Plus Sutures) provide benefits over non-coated sutures in the reduction of SSI risk.
methodsSearches were conducted in fifteen databases. A total of 1,991 records were retrieved. Following deduplication and screening by two independent reviewers, 31 randomized controlled trials in adults and children were included in the review. Similarity of the studies was assessed by narrative review and confirmed by quantitative assessment. A fixed effects meta-analysis of SSI incidence model including all groups of patients estimated a risk ratio of 0.71 (95% confidence interval: 0.64 to 0.79) indicating those in the Plus Sutures group had a 29% reduction in the risk of developing an SSI compared with those in the control group (p < 0.001). Safety outcomes were analysed qualitatively.
resultsThe economic model estimated the use of Plus Sutures to result in average cost savings of £13.63 per patient. Plus Sutures remained cost-saving in all subgroup analyses with cost-savings ranging between £11 (clean wounds) and £140 (non-clean wounds). The environmental impact of SSI is substantial, and the model suggests that the introduction of Plus Sutures could result in potential environmental benefits.
conclusionsThe evidence suggests that Plus Sutures are associated with a reduced incidence of SSI across all surgery types alongside cost savings when compared with standard sutures.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.