Evidence map›Paper›PMID 37789186›Full record

ArticleAMB Express2023

Bioactive metabolites identified from Aspergillus terreus derived from soil.

Menna Fayek, Hassan Y Ebrahim, Mohamed S Abdel-Aziz, Heba Taha, Fatma A Moharram

Open access · goldAbstract read
In one paragraph

Article in AMB Express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Chemical and Biological Investigation of the EndophyticJournal of fungi (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Menna Fayek *Pharmacognosy Department, Faculty of Pharmacy, Helwan University, Cairo, 11795, Egypt.
Hassan Y Ebrahim *Pharmacognosy Department, Faculty of Pharmacy, Helwan University, Cairo, 11795, Egypt.
Mohamed S Abdel-AzizDepartment of Microbial Chemistry Department, Genetic Engineering and Biotechnology Division, National Research Centre, Giza, 12622, Egypt.
Heba TahaBiochemistry and Molecular Biology Department, Faculty of Pharmacy, Helwan University, Cairo, 11795, Egypt.
Fatma A MoharramPharmacognosy Department, Faculty of Pharmacy, Helwan University, Cairo, 11795, Egypt. famoharram1@hotmail.com.ORCID http://orcid.org/0000-0003-3680-7271
Helwan University · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus terreus has been reported to produce many bioactive metabolites that possess potential activities including anti-inflammatory, cytotoxic, and antimicrobial activities. In the present study, we report the isolation and identification of A. terreus from a collected soil sample. The metabolites existing in the microbial ethyl acetate extract were tentatively identified by HPLC/MS and chemically categorized into alkaloids, terpenoids, polyketides, γ-butyrolactones, quinones, and peptides. In addition, a new triglyceride (1) and a diketopiperazine derivative namely asterrine (4), together with two known butyrolactone (2-3) were purified from the extract. The chemical skeleton of the purified compounds was established by comprehensive analysis of their ESI/MS, 1 and 2D-NMR data. The extract and compounds 3,4 exhibited a strong inhibitory activity for the binding of ACE2 to SARS-CoV-2 spike-protein receptor with IC

Indexed as

ACE2 inhibitionAnti-inflammatoryAntimicrobialAspergillus terreusHPLC/MSSecondary metabolites

Identifiers

PMID37789186
PMCPMC10547674
OpenAlexW4387305076

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.