Evidence map›Paper›PMID 37789063›Full record

ArticleScientific reports2023

Probiotic potentials of lactic acid bacteria isolated from Egyptian fermented food.

Fatma I Abdel Tawab, Menna H Abd Elkadr, Amany M Sultan, Ehdaa O Hamed, Ayatollah S El-Zayat, Marwa N Ahmed

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In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
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  3. Review
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  5. Article
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  9. Investigation of probiotic, anticancer and antimicrobial activity of Enterococcus bacteria isolated from the gut microbiota of marine snails.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  10. Potential of Fermented Food-DerivedInternational journal of molecular sciences · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Isolation and characterization of novelJournal of food science and technology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fatma I Abdel Tawab *Oil Crops Biotechnology Lab, Agricultural Genetic Engineering Institute, Agricultural Research Center, Giza, Egypt.
Menna H Abd Elkadr *Microbiology Lab, Research Park, Faculty of Agriculture, Cairo University, Giza, Egypt.
Amany M SultanDepartment of Biochemistry, Toxicology Unit, Animal Health Research Institute, Agricultural Research Center, Giza, Egypt.
Ehdaa O HamedDepartment of Biochemistry, Toxicology Unit, Animal Health Research Institute, Agricultural Research Center, Giza, Egypt.
Ayatollah S El-ZayatDepartment of Microbiology, Faculty of Agriculture, Cairo University, El-Gamaa Street, Giza, 12613, Egypt.
Marwa N AhmedDepartment of Microbiology, Faculty of Agriculture, Cairo University, El-Gamaa Street, Giza, 12613, Egypt. marwa.nabil@agr.cu.edu.eg.ORCID https://orcid.org/0009-0009-3685-6859

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactic acid bacteria (LAB) are of major concern due to their health benefits. Fermented food products comprise variable LAB demonstrating probiotic properties. Discovering and evaluating new probiotics in fermented food products poses a global economic and health importance. Therefore, the present work aimed to investigate and evaluate the probiotic potentials of LAB strains isolated from Egyptian fermented food. In this study, we isolated and functionally characterized 100 bacterial strains isolated from different Egyptian fermented food sources as probiotics. Only four LAB strains amongst the isolated LAB showed probiotic attributes and are considered to be safe for their implementation as feed or dietary supplements. Additionally, they were shown to exert antimicrobial activities against pathogenic bacteria and anticancer effects against the colon cancer cell line Caco-2. The Enterococcus massiliensis IS06 strain was exclusively reported in this study as a probiotic strain with high antimicrobial, antioxidant, and anti-colon cancer activity. Hitherto, few studies have focused on elucidating the impact of probiotic supplementation in vivo. Therefore, in the current study, the safety of the four strains was tested in vivo through the supplementation of rats with potential probiotic strains for 21 days. The results revealed that probiotic bacterial supplementation in rats did not adversely affect the general health of rats. The Lactiplantibacillus plantarum IS07 strain significantly increased the growth performance of rats. Furthermore, the four strains exhibited increased levels of antioxidants such as superoxide dismutase and glutathione in vivo. Consistently, all strains also showed high antioxidant activity of the superoxide dismutase enzyme in vitro. Overall, these findings demonstrated that these isolated potential probiotics harbor desirable characteristics and can be applied widely as feed additives for animals or as dietary supplements for humans to exert their health benefits and combat serious diseases.

Indexed as

Anti-Infective AgentsFermented FoodsLactobacillalesProbioticsAnimalsCaco-2 CellsEgyptHumansRatsSuperoxide DismutaseAnti-Infective AgentsSuperoxide Dismutase

Identifiers

PMID37789063
PMCPMC10547719

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.