ReviewNature communications2023
The uncertain role of substandard and falsified medicines in the emergence and spread of antimicrobial resistance.
Review in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 39 citations in OpenAlex.
- Antimicrobial Use in Dromedary Camels: Off-Label Practices, Welfare Implications, and Antimicrobial Resistance Within a One Health Framework-A Narrative Review.Veterinary sciences · 2026Review
- Substandard and falsified systemic anti-infectives in Peru.Revista peruana de medicina experimental y salud publica · 2026Article
- CAR-macrophage therapy: a novel strategy to overcome antimalarial drug resistance by targeting PfEMP1-mediated adhesion.Malaria journal · 2026Article
- Substandard and Falsified Antibiotics Seized in Belgium: Quality Control Analysis Reveals High Prevalence of WHO Watch List Molecules and Bioavailability Non-Compliance.Antibiotics (Basel, Switzerland) · 2026Article
- Pharmabiome analyses in tandem with chemometrics can help trace the provenance of falsified medicines: A proof-of-concept study.Forensic science international. Genetics · 2026Article
- The urgent need for African research collaboration on medicine quality.Nature communications · 2026Article
- Protocol deviations in medicine quality tests.Bulletin of the World Health Organization · 2026Article
- Sexually transmitted enteric infections in men who have sex with men.Clinical microbiology reviews · 2025Review
- Medicine quality assessment in Nepal using semi randomised sampling and evaluation of a small scale dissolution test and portable Raman spectrometers.Scientific reports · 2025Article
- Transnational Criminal Enterprise: a Qualitative Social Network Analysis of the Production and Trade in Falsified Medicines.Archives europeennes de sociologie. European journal of sociology. Europaisches Archiv fur Soziologie · 2025Article
- Article
- Impact of Biosecurity on Production Performance and Antimicrobial Usage in Broiler Farms in Cameroon.Animals : an open access journal from MDPI · 2025Article
- Substandard and falsified antibiotics are associated with antimicrobial resistance: a retrospective country-level analysis.BMJ global health · 2025Article
- Hide and seek with falsified medicines: Current challenges and physico-chemical and biological approaches for tracing the origin of trafficked products.Forensic science international · 2025Review
- Investigation of CIP quality in over-the-counter drug stores of resource-limited countries: a comparative study in Vietnam and Nigeria.JAC-antimicrobial resistance · 2025Article
- Perceptions and practices on substandard and falsified medicines in humans and animals in Wakiso district, Uganda: A qualitative study.PloS one · 2025Article
- Assessing informal healthcare providers' knowledge of diagnosis and treatment of malaria and diarrhea: evidence from urban informal settlements in Southeast Nigeria.Frontiers in public health · 2025Article
- Article
- Knowledge, attitudes and practices on substandard and falsified medicines for human and animal use in Wakiso district, Uganda.Journal of pharmaceutical policy and practice · 2025Article
- Is price associated with the quality of medicines? Evidence from active pharmaceutical ingredient testing in Nigeria.PloS one · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 4 countries.
Funding
Abstract
Approximately 10% of antimicrobials used by humans in low- and middle-income countries are estimated to be substandard or falsified. In addition to their negative impact on morbidity and mortality, they may also be important drivers of antimicrobial resistance. Despite such concerns, our understanding of this relationship remains rudimentary. Substandard and falsified medicines have the potential to either increase or decrease levels of resistance, and here we discuss a range of mechanisms that could drive these changes. Understanding these effects and their relative importance will require an improved understanding of how different drug exposures affect the emergence and spread of resistance and of how the percentage of active pharmaceutical ingredients in substandard and falsified medicines is temporally and spatially distributed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.