Evidence map›Paper›PMID 37788927›Full record

Observational studyBMJ open2023

Effectiveness of an intervention to increase uptake of voluntary medical male circumcision among men with sexually transmitted infections in Malawi: a preinterventional and postinterventional study.

Mitch M Matoga, Evaristar Kudowa, Beatrice Ndalama, Naomi Bonongwe, Esther Mathiya, Edward Jere, Blessings Kamtambe, Maganizo Chagomerana, Charles Chasela, Sara Jewett and 1 more

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04677374 (Uptake of Voluntary Medical Male Circumcision Among Men Attending a Sexually Transmitted Infections Clinic in Lilongwe, Malawi), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04677374 nacompletednot on this map

Uptake of Voluntary Medical Male Circumcision Among Men Attending a Sexually Transmitted Infections Clinic in Lilongwe, Malawi

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2021 to 2022Enrolled2,242ConditionsHIV Infections, Sexually Transmitted InfectionsArmsStandard of care, Intensified Health Education, SMS/telephonic Tracing, Transportation Reimbursement
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 4 countries.

Mitch M MatogaUniversity of North Carolina Project-Malawi, Lilongwe, Malawi mmatoga@unclilongwe.org.ORCID 0000-0002-6542-8193
Evaristar KudowaUniversity of North Carolina Project-Malawi, Lilongwe, Malawi.
Beatrice NdalamaUniversity of North Carolina Project-Malawi, Lilongwe, Malawi.
Naomi BonongweUniversity of North Carolina Project-Malawi, Lilongwe, Malawi.
Esther MathiyaUniversity of North Carolina Project-Malawi, Lilongwe, Malawi.
Edward JereUniversity of North Carolina Project-Malawi, Lilongwe, Malawi.
Blessings KamtambeUniversity of North Carolina Project-Malawi, Lilongwe, Malawi.
Maganizo ChagomeranaUniversity of North Carolina Project-Malawi, Lilongwe, Malawi.
Charles ChaselaDepartment of Epidemiology and Biostatistics, University of the Witwatersrand, Johannesburg, South Africa.
Sara JewettPublic Health, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-6658-2061
Mina C HosseinipourInstitute of Global Health and Infectious Diseases, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
University of Malawi · MWUniversity of the Witwatersrand · ZAUniversity of North Carolina at Chapel Hill · US

Funding

UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
Malawi HIV Implementation Research Scientist Training Program (MHIRST)D43TW010060 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MINA CHRISTINE HOSSEINIPOUR, Victor Mwapasa · 2015 to 2026
$3.8M
Wits-UNC Partnership: Expanding Capacity in HIV Implementation Science in South AfricaD43TW009774 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PETTIFOR, AUDREY, RAMASWAMY, ROHIT · 2014 to 2023
$3.0M
FIC NIH HHS D43 TW009340FIC NIH HHS D43 TW009774FIC NIH HHS D43 TW010060
6 · The paper itself

Abstract

objectiveTo evaluate the effect a multistrategy demand-creation and linkage intervention on voluntary medical male circumcision (VMMC) uptake, time to VMMC and predictors of VMMC uptake among men with sexually transmitted infections (STIs).

designPragmatic preinterventional and postinterventional quasi-experimental study combined with a prospective observational design.

settingA public and specialised STI clinic in Lilongwe, Malawi. POPULATION: Uncircumcised men who presented to the STI clinic. METHODS AND

interventionThe intervention consisted of transport reimbursement ('R'), intensified health education ('I') and short-messaging services/telephonic tracing ('Te'), abbreviated (RITe). A preintervention phase was conducted at baseline while RITe was rolled-out in the intervention phase in a sequential manner called implementation blocks: 'I' only-block 1; 'I+Te'-block 2 and RITe-block 3.

main outcome measuresPrimary: VMMC uptake and time to VMMC for the full intervention and for each block. Secondary: predictors of VMMC uptake.

resultsA total of 2230 uncircumcised men presented to the STI clinic. The mean age was 29 years (SD±9), 58% were married/cohabiting, HIV prevalence was 6.4% and 43% had urethral discharge. Compared with standard of care (8/514, 1.6%), uptake increased by 100% during the intervention period (55/1716, 3.2%) (p=0.048). 'I' (25/731, 113%, p=0.044) and RITe (17/477, 125%, p=0.044) significantly increased VMMC uptake. The median time to VMMC was shorter during the intervention period (6 days, IQR: 0, 13) compared with standard of care (15 days, IQR: 9, 18). There was no significant incremental effect on VMMC uptake and time to VMMC between blocks. Men with genital warts were 18 times more likely to receive VMMC (adjusted relative risk=18.74, 95% CI: 2.041 to 172.453).

conclusionsOur intervention addressing barriers to VMMC improved VMMC uptake and time to VMMC among uncircumcised men with STIs, an important subpopulation for VMMC prioritisation. TRIAL REGISTRATION NUMBER: NCT04677374.

Indexed as

Circumcision, MaleCondylomata AcuminataHIV InfectionsSexually Transmitted DiseasesAdultHumansMalawiMaleepidemiologyHIV & AIDSpreventive medicinesexually transmitted disease

Identifiers

PMID37788927
PMCPMC10552000
OpenAlexW4387303376

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.