Evidence map›Paper›PMID 37788920›Full record

ArticleOpen heart2023

Impact of gender, ethnicity and social deprivation on access to surgical or transcatheter aortic valve replacement in aortic stenosis: a retrospective database study in England.

Caoimhe T Rice, Sophie Barnett, Shea P O'Connell, Enoch Akowuah, Clare E Appleby, John B Chambers, Benoy N Shah, Daniel J Blackman

Open access · goldAbstract read
In one paragraph

Article in Open heart, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Ethnic variation in aortic root anatomy and prosthesis sizing in TAVI: a UK matched study.European heart journal. Imaging methods and practice · 2025
    Article
  8. Understanding Aortic Stenosis and Transcatheter Aortic Valve Replacement in Women.Structural heart : the journal of the Heart Team · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Misuse of Guidelines Could Disadvantage and Harm Patients.Journal of evidence-based medicine · 2024
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Caoimhe T RiceSpecialty EMR Data, Corevitas, London, UK.ORCID 0000-0003-3017-2279
Sophie BarnettMedtronic International Trading Sarl, Tolochenaz, Switzerland sophie.barnett@medtronic.com.ORCID 0009-0001-5362-172X
Shea P O'ConnellSpecialty EMR Data, Corevitas, London, UK.
Enoch AkowuahSouth Tees Hospitals NHS Foundation Trust, Middlesbrough, UK.ORCID 0000-0002-2429-3579
Clare E ApplebyLiverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool, UK.
John B ChambersGuy's and St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0002-7169-3786
Benoy N ShahUniversity Hospital Southampton NHS Foundation Trust, Southampton, UK.ORCID 0000-0001-9681-7311
Daniel J BlackmanDepartment of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Guy's and St Thomas' NHS Foundation Trust · GBLeeds Teaching Hospitals NHS Trust · GBMedtronic (Switzerland) · CHSouth Tees Hospitals NHS Foundation Trust · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess gender, ethnicity, and deprivation-based differences in provision of aortic valve replacement (AVR) in England for adults with aortic stenosis (AS).

methodsWe retrospectively identified adults with AS from the English Hospital Episode Statistics (HES) between April 2016 and March 2019 and those who subsequently had an AVR. We separately used HES-linked Clinical Practice Research Datalink (CPRD) to identify people with AVR and evaluate the timeliness of their procedure (CPRD-AVR cohort). ORs for AVR in people with an AS diagnosis were estimated using multivariable logistic regression adjusted for age, region and comorbidity. AVR was considered timely if performed electively and without evidence of cardiac decompensation before AVR.

results183 591 adults with AS were identified in HES; of these, 31 436 underwent AVR. The CPRD-AVR cohort comprised 10 069 adults. Women had lower odds of receiving AVR compared with men (OR 0.65; 95% CI 0.63 to 0.66); as did people of black (OR 0.70; 95% CI 0.60 to 0.82) or South Asian (OR 0.75; 95% CI 0.69 to 0.82) compared with people of white ethnicities. People in the most deprived areas were less likely to receive AVR than the least deprived areas (OR 0.8; 95% CI 0.75 to 0.86). Timely AVR occurred in 65% of those of white ethnicities compared with 55% of both those of black and South Asian ethnicities. 77% of the least deprived had a timely procedure compared with 58% of the most deprived; there was no gender difference.

conclusionsIn this large, national dataset, female gender, black or South Asian ethnicities and high deprivation were associated with significantly reduced odds of receiving AVR in England. A lower proportion of people of minority ethnicities or high deprivation had a timely procedure. Public health initiatives may be required to increase clinician and public awareness of unconscious biases towards minority and vulnerable populations to ensure timely AVR for everyone.

Indexed as

Aortic Valve StenosisHeart Valve Prosthesis ImplantationTranscatheter Aortic Valve ReplacementEthnicityFemaleHumansMaleRetrospective StudiesRisk FactorsSocial DeprivationAortic Valve StenosisDelivery of Health CareElectronic Health RecordsHeart Valve Prosthesis ImplantationTranscatheter Aortic Valve Replacement

Identifiers

PMID37788920
PMCPMC10565153
OpenAlexW4387314414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.