Evidence map›Paper›PMID 37788620›Full record

ArticleJournal of addiction medicine

Nonopioid Substance Use among Patients Who Recently Initiated Office-based Buprenorphine Treatment.

Karen L Dugosh, Michelle R Lent, S Brook Burkley, Conor M K Millard, James R McKay, Kyle M Kampman

Open access · greenAbstract read
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Karen L DugoshFrom the Research and Evaluation Group, Public Health Management Corporation, Philadelphia, PA (KLD, SBB, CMKM); School of Professional and Applied Psychology, Philadelphia College of Osteopathic Medicine, Philadelphia, PA (MRL); Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (JRM, KMK).
Michelle R Lent
S Brook Burkley
Conor M K Millard
James R McKay
Kyle M Kampman
Philadelphia College of Osteopathic Medicine · US

Funding

Patient-Centered Outcomes Research Institute OBOT-2018C2-13158
6 · The paper itself

Abstract

objectivesMedications for opioid use disorder (MOUDs) like buprenorphine are a first-line treatment for individuals who have opioid use disorder (OUD); however, these medications are not designed to impact the use of other classes of drugs. This descriptive study provides up-to-date information about nonopioid substance use among patients who recently initiated office-based buprenorphine treatment for OUD using data from 2 ongoing clinical trials.

methodsThe study sample was composed of 257 patients from 6 federally qualified health centers in the mid-Atlantic region who recently (i.e., within the past 28 days) initiated office-based buprenorphine treatment between July 2020 and May 2022. After the screening and informed consent processes, participants completed a urine drug screen and psychosocial interview as a part of the study baseline assessment. Descriptive analyses were performed on urine drug screen results to identify the prevalence and types of substances detected.

resultsMore than half of participants provided urine specimens that were positive for nonopioid substances, with marijuana (37%, n = 95), cocaine (22%, n = 56), and benzodiazepines (11%, n = 28) detected with the highest frequencies.

conclusionsA significant number of participants used nonopioid substances after initiating buprenorphine treatment, suggesting that some patients receiving MOUDs could potentially benefit from adjunctive psychosocial treatment and supports to address their nonopioid substance use.

Indexed as

BuprenorphineCocaineOpioid-Related DisordersAnalgesics, OpioidHumansOpiate Substitution TreatmentAnalgesics, OpioidBuprenorphineCocaine

Identifiers

PMID37788620
PMCPMC10583252
OpenAlexW4366236434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.