Evidence map›Paper›PMID 37788573›Full record

ReviewAnnual review of psychology2024

What Does the Human Olfactory System Do, and How Does It Do It?

Gülce Nazlı Dikeçligil, Jay A Gottfried

Abstract readReview
In one paragraph

Review in Annual review of psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Smell Is Emotion.Brain sciences · 2025
    Article
  9. One Biology and the Status of Humans.Animals : an open access journal from MDPI · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. IMPAIRED OLFACTORY FUNCTION IN SUBSTANCE USE DISORDER.medRxiv : the preprint server for health sciences · 2025
    Article
  16. Review
  17. Exploring LinearJournal of medicinal chemistry · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gülce Nazlı DikeçligilDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; email: nazdikec@pennmedicine.upenn.edu, jaygottf@pennmedicine.upenn.edu.
Jay A GottfriedDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; email: nazdikec@pennmedicine.upenn.edu, jaygottf@pennmedicine.upenn.edu.

Funding

Spatiotemporal Mechanisms of Olfactory Processing in the Human BrainR01DC018075 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI GOTTFRIED, JAY A · 2020 to 2024
$2.2M
Behavioral and Neural Substrates of Odor-Guided Navigation in the Human BrainU01DC019405 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI GOTTFRIED, JAY A · 2023 to 2025
$1.4M
Behavioral and Neural Substrates of Odor-Guided Navigation in the Human BrainR01DC019405 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI Jay A Gottfried · 2022 to 2026
$924k
NIDCD NIH HHS R01 DC018075NIDCD NIH HHS R01 DC019405NIDCD NIH HHS U01 DC019405
6 · The paper itself

Abstract

Historically, the human sense of smell has been regarded as the odd stepchild of the senses, especially compared to the sensory bravado of seeing, touching, and hearing. The idea that the human olfaction has little to contribute to our experience of the world is commonplace, though with the emergence of COVID-19 there has rather been a sea change in this understanding. An ever increasing body of work has convincingly highlighted the keen capabilities of the human nose and the sophistication of the human olfactory system. Here, we provide a concise overview of the neuroscience of human olfaction spanning the last 10-15 years, with focus on the peripheral and central mechanisms that underlie how odor information is processed, packaged, parceled, predicted, and perturbed to serve odor-guided behaviors. We conclude by offering some guideposts for harnessing the next decade of olfactory research in all its shapes and forms.

Indexed as

SmellHumansfMRIfunctional magnetic resonance imaginghuman olfactionhuman peripheral olfactory systemintracranial electroencephalogramodor perceptionsensory neuroscience

Identifiers

PMID37788573
PMCPMC12931680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.