Evidence map›Paper›PMID 37788495›Full record

ReviewThe Journal of infectious diseases2023

Advances and Challenges in Molecular Imaging of Viral Infections.

Chuen-Yen Lau, Neysha Martinez-Orengo, Anna Lyndaker, Kelly Flavahan, Reed F Johnson, Swati Shah, Dima A Hammoud

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Radiolabeled Antimicrobials for Infection Imaging: A Scoping Review.International journal of molecular sciences · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Reporter-expressing viruses for antiviral drug discovery research.Frontiers in cellular and infection microbiology · 2025
    Review
  7. Review
  8. Nuclear Medicine Imaging Tools in Fever of Unknown Origin: Time for a Revisit and Appropriate Use Criteria.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  9. Monitoring RVFV Infection Using Bioluminescent Reporter Viruses In Vivo.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chuen-Yen LauHIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0002-4337-8885
Neysha Martinez-OrengoRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Anna LyndakerRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Kelly FlavahanCenter for Infection and Inflammation Imaging Research, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Reed F JohnsonSARS-CoV-2 Virology Core, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Swati ShahRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Dima A HammoudRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
National Institutes of Health Clinical Center · USNational Institutes of Health · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular imaging of viral infection, using a variety of advanced imaging techniques such as optical and nuclear imaging, can and has been used for direct visualization of the virus as well as assessment of virus-host interactions. Unlike imaging of other pathogens such as bacteria and fungi, challenging aspects of imaging viral infections include the small size of viruses, the complexity of viral infection animal models (eg, species dependence), and the high-level containment needs for many high-consequence pathogens, among others. In this review, using representative viral infections, we discuss how molecular imaging can reveal real-time infection dynamics, improve our understanding of disease pathogenesis, and guide optimization of treatment and prevention strategies. Key findings from human and animal studies are highlighted.

Indexed as

Virus DiseasesVirusesAnimalsHost Microbial InteractionsHumansMolecular ImagingEbolahigh-consequence infectionHIVinfluenzamolecular imagingPET scanreporter virusRSVviral infection

Identifiers

PMID37788495
PMCPMC10547465
OpenAlexW4387312404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.