Evidence map›Paper›PMID 37788484›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2023

The Effects of Midlife Acute and Chronic Stressors on Black-White Differences in Cognitive Decline.

Uchechi A Mitchell, Benjamin A Shaw, Jacqueline M Torres, Lauren L Brown, Lisa L Barnes

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Uchechi A MitchellDivision of Community Health Sciences, School of Public Health, University of Illinois Chicago, Chicago, Illinois, USA.ORCID 0000-0003-1675-1119
Benjamin A ShawDivision of Community Health Sciences, School of Public Health, University of Illinois Chicago, Chicago, Illinois, USA.ORCID 0000-0002-4756-495X
Jacqueline M TorresDepartment of Epidemiology & Biostatistics, School of Medicine, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-1579-6107
Lauren L BrownLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California, USA.ORCID 0000-0002-1681-8267
Lisa L BarnesDepartment of Neurological Sciences and Rush Alzheimer's Disease Center at Rush Medical College, Chicago, Illinois, USA.ORCID 0000-0002-0072-9817

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
The Role of Mid-life Psychosocial Stressors, Social Resources and Physiological Dysregulation in Understanding Race Differences in Cognitive DeclineR21AG065654 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MITCHELL, UCHECHI ACHOLONU · 2020 to 2020
$327k
NIA NIH HHS R21 AG065654NIA NIH HHS U01 AG009740NIA NIH HHS U01AG009740NIH HHS 1R21AG065654-01A1
6 · The paper itself

Abstract

objectivesMidlife stressors may be particularly consequential for cognitive performance and disparities in cognitive decline. This study examined Black-White differences in trajectories of cognition among middle-aged adults and the effects of acute and chronic stressors on these trajectories.

methodsData come from 4,011 cognitively healthy individuals aged 51-64 (620 Black and 3,391 White) who participated in the 2006-2018 waves of the Health and Retirement Study. Stressors included a count of recent life events and measures of financial strain and everyday discrimination. Global cognition was assessed using a modified version of the Telephone Interview for Cognitive Status. Linear mixed models with random slopes and intercepts assessed change in cognition over time. Race-by-time, race-by-stressor, time-by-stressor, and race-by-stressor-by-time interactions were assessed as were quadratic terms for time and each stressor.

resultsAfter adjusting for sociodemographic, health behaviors, and health-related factors, Black respondents had lower initial cognitive performance scores (b = -1.75, p < .001) but experienced earlier but slower decline in cognitive performance over time (Black × Time2 interaction: b = 0.02, p < .01). Financial strain, discrimination, and recent life events each had distinct associations with cognitive performance but did not influence racial differences in levels of or change in cognition over time. DISCUSSION: Middle-aged Black adults have lower initial cognition levels and experience earlier but less accelerated cognitive decline compared to White middle-aged adults. Midlife acute and chronic stressors influence baseline cognition but do so in different ways. Future research should examine the influence of other stressors on racial differences in cognitive decline at other points in the life course.

Indexed as

Black or African AmericanCognitive DysfunctionStress, PsychologicalWhiteCognitionHumansMiddle AgedAfrican AmericansHealth and Retirement StudyHealth DisparitiesMemoryStress process

Identifiers

PMID37788484
PMCPMC10699748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.