ArticleAmerican journal of respiratory and critical care medicine2023
Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function.
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In one paragraph
Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Somatic mutation analysis of mucin genes and pathways in idiopathic pulmonary fibrosis.American journal of respiratory and critical care medicine · 2026Article
- Single-cell atlas of human lung aging identifies cell type dyssynchrony and increased transcriptional entropy.Nature communications · 2026Article
- Age-related diseases as a testbed for anti-aging therapeutics: the case of idiopathic pulmonary fibrosis.Aging · 2025Review
- Decoding the complexity: mechanistic insights into comorbidities in idiopathic pulmonary fibrosis.The European respiratory journal · 2025Review
- Clonal haematopoiesis of indeterminate potential: a risk factor for future exacerbation in patients with COPD.ERJ open research · 2025Article
- Genome-wide mutagenesis reported in systemic sclerosis.Nature reviews. Rheumatology · 2025Article
- Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors.Nature cancer · 2024Article
- Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.American journal of respiratory and critical care medicine · 2024Review
- The guardians of pulmonary harmony: alveolar macrophages orchestrating the symphony of lung inflammation and tissue homeostasis.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function.American journal of respiratory and critical care medicine · 2023Article
- Somatic Mutations: The Next Frontier in Demystifying Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis?American journal of respiratory and critical care medicine · 2023Article
Corrections and comments
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Authors and funding
21 authors at 13 institutions in 1 country.
Jeong H YunChanning Division of Network Medicine and.ORCID 0000-0002-4361-8295
M A Wasay KhanDivision of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee.
Auyon GhoshPulmonary Critical Care and Sleep Medicine, Upstate Medical University, Syracuse, New York.ORCID 0000-0003-0334-4039
Brian D HobbsChanning Division of Network Medicine and.ORCID 0000-0001-9564-0745
Peter J CastaldiChanning Division of Network Medicine and.
Craig P HershChanning Division of Network Medicine and.ORCID 0000-0002-1342-4334
Peter G MillerHarvard Medical School, Boston, Massachusetts.
Carlyne D CoolDivision of Pathology, Department of Medicine, University of Colorado, Aurora, Colorado.
Frank SciurbaDivision of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Lucas BarwickEmmes, Frederick, Maryland.
Andrew H LimperDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Kevin FlahertyDivision of Pulmonary and Critical Care Medicine, University of Michigan Health System, Ann Arbor, Michigan.
Gerard J CrinerThoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.
Kevin BrownDepartment of Medicine, National Jewish Health, Denver, Colorado.
Robert WiseDepartment of Medicine, Johns Hopkins Medicine, Baltimore, Maryland; and.ORCID 0000-0002-8353-2349
Fernando MartinezDepartment of Medicine, Weill Cornell Medical College, New York, New York.
Edwin K SilvermanChanning Division of Network Medicine and.
Dawn DeMeoChanning Division of Network Medicine and.
NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
Michael H ChoChanning Division of Network Medicine and.ORCID 0000-0002-4907-1657
Alexander G BickDivision of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee.
Brigham and Women's Hospital · USHarvard University · USVanderbilt University · USCornell University · USEmmes (United States) · USJohns Hopkins University · USMayo Clinic · USMichigan United · USNational Jewish Health · USSUNY Upstate Medical University · USTemple University · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Pittsburgh · US
Funding
Respiratory Computational Discovery CoreP01HL114501 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHOI, MARY E · 2013 to 2025
$24.9MGenetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7MUsing Integrative Genomics To Identify and Characterize Emphysema-Associated eQTLR01HL124233 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CASTALDI, PETER · 2014 to 2024
$7.1MGenetic and Functional Dissection of a Cluster of COPD GWAS Signals on Chromosome 4qR01HL147148 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., SILVERMAN, EDWIN K · 2019 to 2022
$3.5MIdentifying Protein-Protein Network Interactions between COPD Susceptibility GenesR01HL152728 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K, WEI, WENYI · 2021 to 2024
$3.2MClinical Implications, Genomics, and Transcriptions of Mucus Plugging in SmokersR01HL149861 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHO, MICHAEL H., DIAZ, ALEJANDRO · 2020 to 2023
$3.2MUncovering the genetically-driven differential susceptibility to chronic obstructive pulmonary disease and pulmonary fibrosisR01HL162813 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHAEL H. CHO · 2023 to 2026
$3.1MIntegrative genomic, transcriptomic and proteomic studies of pulmonary function and COPDR01HL153248 · NHLBI · UNIVERSITY OF VIRGINIA · PI CHO, MICHAEL H., MANICHAIKUL, ANI WANG · 2021 to 2024
$2.8MTargeting Clonal Hematopoiesis of Indeterminate Potential Using Human GeneticsDP5OD029586 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BICK, ALEXANDER · 2020 to 2024
$2.3MNetworks Tools to Understand Sex- and Gender-Specific Drivers of DiseaseR01HG011393 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMEO, DAWN L, QUACKENBUSH, JOHN · 2021 to 2024
$2.1MProspective Health Outcomes and Inflammatory Biomarkers Associated with e-Cigarette UseR01HL147326 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CASTALDI, PETER · 2019 to 2021
$1.5MThe role of COPD genetic risk factor HHIP on lymphocytic inflammationK08HL146972 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI YUN, JEONG H · 2020 to 2024
$848kNHGRI NIH HHS R01 HG011393NHLBI NIH HHS K08 HL146972NHLBI NIH HHS K08HL146972NHLBI NIH HHS K08 HL168205NHLBI NIH HHS P01 HL114501NHLBI NIH HHS R01 HL124233NHLBI NIH HHS R01 HL147148NHLBI NIH HHS R01 HL147326NHLBI NIH HHS R01 HL149861NHLBI NIH HHS R01 HL152728NHLBI NIH HHS R01 HL153248NHLBI NIH HHS R01 HL162813NHLBI NIH HHS R21 HL156122NHLBI NIH HHS U01 HL089856NIA NIH HHS DP5 OD029586NIH HHS DP5 OD029586
Abstract
PubMed holds no abstract for this paper.
Indexed as
Idiopathic Pulmonary FibrosisPulmonary Disease, Chronic ObstructiveHumansLungMutationRespiratory Physiological Phenomenachronic obstructive pulmonary diseaseidiopathic pulmonary fibrosissomatic mutation
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.