Evidence map›Paper›PMID 37788369›Full record

Observational studyCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2023

Unraveling Racial Disparities in Supportive Care Medication Use among End-of-Life Pancreatic Cancer Patients: Focus on Pain Management and Psychiatric Therapies.

John M Allen, MegCholack Awunti, Yi Guo, Jiang Bian, Sherise C Rogers, Lisa Scarton, David L DeRemer, Diana J Wilkie

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

John M AllenDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Orlando, Florida.ORCID 0000-0002-0033-4508
MegCholack AwuntiDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Orlando, Florida.ORCID 0000-0002-8841-0180
Yi GuoDepartment of Health Outcomes & Biomedical Informatics, University of Florida College of Medicine, Gainesville, Florida.ORCID 0000-0003-0587-4105
Jiang BianDepartment of Health Outcomes & Biomedical Informatics, University of Florida College of Medicine, Gainesville, Florida.ORCID 0000-0002-2238-5429
Sherise C RogersDivision of Hematology & Oncology, University of Florida College of Medicine, Gainesville, Florida.ORCID 0000-0002-4886-3169
Lisa ScartonDepartment of Family, Community, and Health Systems Science, University of Florida College of Nursing, Gainesville, Florida.ORCID 0000-0003-1255-0811
David L DeRemerDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Florida.ORCID 0000-0002-2207-9552
Diana J WilkieDepartment of Biobehavioral Nursing Science, University of Florida College of Nursing, Gainesville, Florida.ORCID 0000-0002-3954-8933
University of Florida Health · USFlorida College · USUniversity of Florida · USAmerican Association of Colleges of Pharmacy · US

Funding

Tissue Modeling & Drug Development Shared Resources CoreU54CA233444 · NCI · UNIVERSITY OF FLORIDA · PI Chanita A. Hughes-Halbert, Tianze Jiao · 2018 to 2026
$12.1M
Tissue Modeling CoreU54CA233465 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Bodour Salhia · 2018 to 2026
$11.9M
Tissue Modeling CoreU54CA233396 · NCI · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI Gebre-Egziabher Kiros · 2018 to 2026
$9.8M
The benefits and harms of lung cancer screening in FloridaR01CA246418 · NCI · UNIVERSITY OF FLORIDA · PI BIAN, JIANG, GUO, YI · 2020 to 2023
$1.7M
Using Electronic Health Records from a Large Clinical Data Research Network to Understand Cancer Burden and Cancer Risks Among Transgender and Gender Nonconforming (TGNC) IndividualsR21CA245858 · NCI · UNIVERSITY OF FLORIDA · PI BIAN, JIANG, GUO, YI · 2020 to 2021
$773k
Examining the determinants and consequences of supportive care medication use disparities in patients with pancreatic cancer: A sequential mixed-methods approachR01MD019684 · NIMHD · UNIVERSITY OF FLORIDA · PI ALLEN, JOHN M · 2024 to 2024
$515k
Optimizing the Population Representativeness of Older Adults in Cancer TrialsR21CA253394 · NCI · UNIVERSITY OF FLORIDA · PI BIAN, JIANG, GUO, YI · 2021 to 2021
$392k
NCI NIH HHS HHSN261201800009CNCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015CNCI NIH HHS HHSN261201800015INCI NIH HHS HHSN261201800032CNCI NIH HHS HHSN261201800032INCI NIH HHS R01 CA246418NCI NIH HHS R21 CA245858NCI NIH HHS R21 CA253394NCI NIH HHS U54 CA233396NCI NIH HHS U54 CA233444NCI NIH HHS U54 CA233465NIMHD NIH HHS R01 MD019684
6 · The paper itself

Abstract

backgroundSupportive care medication use differences may contribute to racial disparities observed in health-related quality of life in patients with pancreatic cancer.

methodsIn this observation study using the Surveillance, Epidemiology, and End Results-Medicare linked database, we sought to examine supportive care medication use disparities in patients with pancreatic cancer from 2005 to 2017 by race and ethnicity.

resultsAmong 74,309 patients included in the final analysis, racial and ethnic disparities in the use of supportive care medications were identified. After adjustment for confounding factors and compared with non-Hispanic Whites, minorities had significantly less use of opioids [Black: adjusted OR (aOR), 0.84; 95% confidence interval (CI), 0.79-0.88; Asian: aOR, 0.84; 95% CI, 0.79-0.90), and skeletomuscular relaxants (Black: aOR, 0.90; 95% CI, 0.82-0.99; Hispanic: aOR, 0.82; 95% CI, 0.74-0.91; Asian: aOR, 0.59; 95% CI, 0.51-0.68), and increased use of non-opioid analgesics (Hispanic: aOR, 1.16; 95% CI, 1.01-1.14; Asian: aOR, 1.37; 95% CI, 1.26-1.49). Racial and ethnic minorities had less use of antidepressants (Black: aOR, 0.56; 95% CI, 0.53-0.59; Hispanic: aOR, 0.77; 95% CI, 0.73-0.82; Asian: aOR, 0.47; 95% CI, 0.44-0.51), anxiolytics (Black: aOR, 0.78; 95% CI, 0.74-0.82; Hispanic: aOR, 0.66; 95% CI, 0.62-0.71; Asian: aOR, 0.52; 95% CI, 0.48-0.57), and antipsychotics (Hispanic: aOR, 0.90; 95% CI, 0.82-0.99; Asian: aOR, 0.84; 95% CI, 0.74-0.95).

conclusionsRacial and ethnic disparities in the use of supportive care medications among patients with pancreatic cancer were observed, with the differences unexplained by sociodemographic factors. IMPACT: Future studies should identify strategies to promote equitable use of supportive care medications among racial minorities and explore factors that may influence their use in these populations.

Indexed as

Pain ManagementPancreatic NeoplasmsAgedDeathHealthcare DisparitiesHumansMedicareQuality of LifeUnited States

Identifiers

PMID37788369
PMCPMC10690138
OpenAlexW4387299424

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.