ArticleProceedings of the National Academy of Sciences of the United States of America2023
The duplication of genomes and genetic networks and its potential for evolutionary adaptation and survival during environmental turmoil.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Extreme Polyploidy Reveals Functional Trade-Offs in Plant Drought Responses.Plant, cell & environment · 2026Article
- Non-coding DNA dynamics and its roles as a physical barrier in genome safeguarding across early development and evolution.Heredity · 2026Review
- A milestone in resolving the polyploid paradox.Plant diversity · 2026Article
- Ecological opportunity and the onset of polyploid niche expansion waves.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Polyploidy: A macromutational force pushing bioeconomic developments.Proceedings of the National Academy of Sciences of the United States of America · 2026Review
- Plastid and nuclear phylogenomics of Cyphostemma (Vitaceae) provide new insights into genome size evolution across sub-Saharan Africa.Journal of integrative plant biology · 2026Article
- Horizontal gene transfer and diploidy illuminate evolution and stress adaptation in oleaginous Scenedesmaceae (Chlorophyta).Nature communications · 2026Article
- Integrative bioinformatics analysis of potential convergent evolution in tardigrade stress-response proteins.Stress biology · 2026Article
- Gene duplication is associated with gene diversification and potential neofunctionalization in lung cancer evolution.Genome research · 2026Article
- Evolutionary analysis ofFrontiers in plant science · 2026Article
- Whole-Genome Duplication Reshapes Adaptation: Autotetraploid Arabidopsis arenosa Leverages its High Genetic Variation to Compensate for Selection Constraints.Molecular biology and evolution · 2025Article
- Convergent subgenome dominance but with lineage-specific functional divergence of homoeologs during cave adaptation: insights from full-length transcriptomes of Sinocyclocheilus species.Frontiers in zoology · 2025Article
- Genome Architecture and Speciation in Plants and Animals.Molecular ecology · 2025Review
- Climate change and plant genomic plasticity.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Reticulate allopolyploidy and subsequent dysploidy drive evolution and diversification in the cotton family.Nature communications · 2025Article
- Expression pattern changes of three homeologs in chemokine activity enhance antiviral response to herpesvirus infection in a newly synthesized alloheptaploid.BMC genomics · 2025Article
- Genomic and evolutionary evidence for drought adaptation of allopolyploid Brachypodium hybridum.Journal of experimental botany · 2025Article
- Quantifying Transcriptome Turnover on Phylogenies by Modeling Gene Expression as a Binary Trait.Molecular biology and evolution · 2025Article
- A chromosome-level genome assembly of the varied leaved jewelflower, Streptanthus diversifolius, reveals a recent whole genome duplication.G3 (Bethesda, Md.) · 2025Article
- Parallel Selection in Domesticated Atlantic Salmon from Divergent Founders Including on Whole-Genome Duplication-derived Homeologous Regions.Genome biology and evolution · 2025Article
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8 authors.
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Abstract
The importance of whole-genome duplication (WGD) for evolution is controversial. Whereas some view WGD mainly as detrimental and an evolutionary dead end, there is growing evidence that polyploidization can help overcome environmental change, stressful conditions, or periods of extinction. However, despite much research, the mechanistic underpinnings of why and how polyploids might be able to outcompete or outlive nonpolyploids at times of environmental upheaval remain elusive, especially for autopolyploids, in which heterosis effects are limited. On the longer term, WGD might increase both mutational and environmental robustness due to redundancy and increased genetic variation, but on the short-or even immediate-term, selective advantages of WGDs are harder to explain. Here, by duplicating artificially generated Gene Regulatory Networks (GRNs), we show that duplicated GRNs-and thus duplicated genomes-show higher signal output variation than nonduplicated GRNs. This increased variation leads to niche expansion and can provide polyploid populations with substantial advantages to survive environmental turmoil. In contrast, under stable environments, GRNs might be maladaptive to changes, a phenomenon that is exacerbated in duplicated GRNs. We believe that these results provide insights into how genome duplication and (auto)polyploidy might help organisms to adapt quickly to novel conditions and to survive ecological uproar or even cataclysmic events.
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