Evidence map›Paper›PMID 37788310›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Shear force enhances adhesion of

Jessica-Jae S Palalay, Ahmet N Simsek, Jessie L Reed, Matthias D Koch, Benedikt Sabass, Joseph E Sanfilippo

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  4. Detoxification of host-relevant HbioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
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  11. A shear-induced limit on bacterial surface adhesion in fluid flow.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  12. Review
  13. Article
  14. Flagellum-driven motility enhancesApplied and environmental microbiology · 2025
    Article
  15. Review
  16. Article
  17. Bacterial species with different nanocolony morphologies have distinct flow-dependent colonization behaviors.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jessica-Jae S PalalayDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.ORCID 0009-0009-9400-7134
Ahmet N SimsekDepartment of Veterinary Sciences, Institute for Infectious Diseases and Zoonoses, Ludwig-Maximilians-Universität München, Munich 80752, Germany.
Jessie L ReedDepartment of Biology, Texas A&M University, College Station, TX 77843.ORCID 0000-0001-6477-0168
Matthias D KochDepartment of Biology, Texas A&M University, College Station, TX 77843.ORCID 0000-0003-4408-9900
Benedikt SabassDepartment of Veterinary Sciences, Institute for Infectious Diseases and Zoonoses, Ludwig-Maximilians-Universität München, Munich 80752, Germany.
Joseph E SanfilippoDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Ludwig-Maximilians-Universität München · DETexas A&M University · USUniversity of Illinois Urbana-Champaign · US

Funding

Mechanobehavior of Pseudomonas aeruginosa in shear flowK22AI151263 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SANFILIPPO, JOSEPH · 2021 to 2022
$267k
NIAID NIH HHS K22 AI151263
6 · The paper itself

Abstract

Fluid flow is thought to prevent bacterial adhesion, but some bacteria use adhesins with catch bond properties to enhance adhesion under high shear forces. However, many studies on bacterial adhesion either neglect the influence of shear force or use shear forces that are not typically found in natural systems. In this study, we use microfluidics and single-cell imaging to examine how the human pathogen

Indexed as

Fimbriae, BacterialPseudomonas aeruginosaAdhesins, BacterialBacterial AdhesionFimbriae ProteinsHumansPhysical PhenomenaAdhesins, BacterialFimbriae ProteinsadhesionmicrofluidicsPseudomonas aeruginosashear forcetype IV pili

Identifiers

PMID37788310
PMCPMC10576114
OpenAlexW4387303310

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.