ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024
Content validity of the EQ-5D-5L with skin irritation and self-confidence bolt-ons in patients with atopic dermatitis: a qualitative think-aloud study.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 15 citations in OpenAlex.
- Adipose tissue-derived stem cell exosomes enhance skin barrier function and show exploratory associations with the skin mycobiome in aging skin.Journal of microbiology (Seoul, Korea) · 2026Trial
- Psychometric benefits of adding four bolt-ons (skin irritation, self-confidence, social relationships and sleep) to EQ-5D-5L compared to PROMIS-29 and Skindex-16 in patients with psoriasis and atopic dermatitis.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Comparative performance of EQ-5D-5L bolt-ons in China and the Netherlands: results from the EQ-DAPHNIE project.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Thinking-aloud methodology applied to health questionnaire development and validation: a scoping review.BMC medical research methodology · 2026Article
- Psychometric properties of four FACE-Q Aesthetics scales in patients planning and undergoing minimally invasive facial cosmetic procedures.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Qualitative testing of the EQ-HWB-9 with a 'blank' EQ-HWB VAS and EQ-5D-5L with skin bolt-ons in a rare genetic skin disease population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Testing culturally relevant EQ-5D-5L bolt-ons for the Chinese general population: first quantitative phase of a mixed methods study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Therapist-Guided Versus Self-Guided Forest Immersion: Comparative Efficacy on Short-Term Mental Health and Economic Value.Behavioral sciences (Basel, Switzerland) · 2025Article
- Psychometric testing of two respiratory bolt-on items to EQ-5D-5L in patients with obstructive airway diseases.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Psychometric benefits of adding bolt-ons to the EQ-5D-5L in populations undergoing minimally invasive cosmetic procedures.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Article
- Patient Validation of Estimation of Health Utility Values in Alopecia Areata.PharmacoEconomics - open · 2025Article
- Comparing EQ-5D-5L, PROPr, SF-6D and TTO utilities in patients with chronic skin diseases.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Article
- Qualitative evidence on EQ-5D-5L skin irritation and self-confidence bolt-ons in Darier's disease and Hailey-Hailey disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Exploring the content validity of the EQ-5D-5L and four bolt-ons (skin irritation, self-confidence, sleep, social relationships) in atopic dermatitis and chronic urticaria.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- The added value of the cognition, dining, gastrointestinal problems, sleep and tiredness bolt-on dimensions to the EQ-5D-5L in patients with coeliac disease.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTwo bolt-on dimensions (skin irritation, self-confidence) have been developed for the EQ-5D-5L to improve its content validity and responsiveness in psoriasis. However, the two bolt-ons are not strictly psoriasis-specific and are potentially relevant in other skin conditions. This study aims to explore the content validity of the EQ-5D-5L with two bolt-ons in patients with atopic dermatitis (AD).
methodsIn 2021-2022, qualitative, semi-structured interviews were conducted with 20 adult AD patients at a university dermatology clinic in Hungary. We aimed for a heterogeneous sample in terms of age, gender, education and disease severity. Patients completed the EQ-5D-5L with two bolt-ons using a think-aloud protocol. Probing questions were posed to investigate item relevance, potential conceptual overlaps, missing concepts and the appropriateness of the recall period. Interview transcripts were subjected to thematic analysis.
resultsThe EQ-5D-5L with the two bolt-ons covered the most important aspects of health-related quality of life in AD patients. Most patients found both the skin irritation and self-confidence bolt-ons relevant. Fifteen potential missing concepts were identified, but only two (social relationships, judgement by others) were identified by more than one patient. A smaller conceptual overlap was found between the skin irritation and pain/discomfort dimensions in 7 patients (35%). Half the patients expressed a preference for a recall period of 1 week rather than of 'today'.
conclusionsThe EQ-5D-5L with skin irritation and self-confidence bolt-ons showed good relevance, comprehensiveness and comprehensibility in patients with AD. However, in terms of comprehensiveness, social relationships and judgement by others (stigma) may be missing from the questionnaire.
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