Evidence map›Paper›PMID 37787672›Full record

ReviewRadiology2023

Clinical Applications of Photon-counting CT: A Review of Pioneer Studies and a Glimpse into the Future.

Philippe C Douek, Sara Boccalini, Edwin H G Oei, David P Cormode, Amir Pourmorteza, Loic Boussel, Salim A Si-Mohamed, Ricardo P J Budde

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed.

  1. Trial
  2. [Contrast agent strategies in elective oncological imaging].Radiologie (Heidelberg, Germany) · 2026
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Philippe C Douek *From the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).ORCID 0000-0002-5096-4698
Sara Boccalini *From the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).
Edwin H G OeiFrom the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).ORCID 0000-0003-3727-3427
David P CormodeFrom the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).
Amir PourmortezaFrom the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).ORCID 0000-0001-7149-5424
Loic BousselFrom the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).ORCID 0000-0001-9053-8127
Salim A Si-MohamedFrom the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).ORCID 0000-0003-0314-4010
Ricardo P J BuddeFrom the University of Lyon, INSA-Lyon, Claude Bernard Lyon 1 University, UJM-Saint Etienne, CNRS, Inserm, Villeurbanne, France (P.C.D., L.B., S.A.S.M.); Department of Cardiovascular and Thoracic Radiology, Louis Pradel Hospital, Hospices Civils de Lyon, 59 Boulevard Pinel, 69500 Bron, France (P.C.D., S.B., L.B., S.A.S.M.); Claude Bernard Lyon 1 University, Villeurbanne, France (S.B.); Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (E.H.G.O., R.P.J.B.); Department of Radiology, University of Pennsylvania, Philadelphia, Pa (D.P.C.); Department of Radiology and Imaging Sciences, Emory University, Atlanta, Ga (A.P.); Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga (A.P.); and Winship Cancer Institute, Atlanta, Ga (A.P.).ORCID 0000-0003-3792-615X

Funding

Renally clearable ytterbium nanoparticle contrast agents for spectral photon counting computed tomographyR21EB030373 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI CORMODE, DAVID PETER · 2021 to 2022
$447k
NIBIB NIH HHS R21 EB030373
6 · The paper itself

Abstract

CT systems equipped with photon-counting detectors (PCDs), referred to as photon-counting CT (PCCT), are beginning to change imaging in several subspecialties, such as cardiac, vascular, thoracic, and musculoskeletal radiology. Evidence has been building in the literature underpinning the many advantages of PCCT for different clinical applications. These benefits derive from the distinct features of PCDs, which are made of semiconductor materials capable of converting photons directly into electric signal. PCCT advancements include, among the most important, improved spatial resolution, noise reduction, and spectral properties. PCCT spatial resolution on the order of 0.25 mm allows for the improved visualization of small structures (eg, small vessels, arterial walls, distal bronchi, and bone trabeculations) and their pathologies, as well as the identification of previously undetectable anomalies. In addition, blooming artifacts from calcifications, stents, and other dense structures are reduced. The benefits of the spectral capabilities of PCCT are broad and include reducing radiation and contrast material dose for patients. In addition, multiple types of information can be extracted from a single data set (ie, multiparametric imaging), including quantitative data often regarded as surrogates of functional information (eg, lung perfusion). PCCT also allows for a novel type of CT imaging, K-edge imaging. This technique, combined with new contrast materials specifically designed for this modality, opens the door to new applications for imaging in the future.

Indexed as

ArteriesTomography, X-Ray ComputedArtifactsBronchiContrast MediaHumansContrast Media

Identifiers

PMID37787672
PMCPMC10623209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.