Evidence map›Paper›PMID 37786898›Full record

ArticleSAGE open medicine2023

Comparison of triamcinolone with pentoxifylline and vitamin E efficacy in the treatment of stage 2 and 3 oral submucous fibrosis: A randomized clinical trial.

Saeed Ullah Shah, Seeme Nigar, Rahima Yousofi, Afsheen Maqsood, Sara Altamash, Abhishek Lal, Zarak Khan, Naseer Ahmed, Artak Heboyan

Open access · goldAbstract read
In one paragraph

Article in SAGE open medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Saeed Ullah ShahDepartment of Oral Medicine, Altamash Institute of Dental Medicine, Karachi, Pakistan.
Seeme NigarDepartment of Oral Pathology, Altamash Institute of Dental Medicine, Karachi, Pakistan.
Rahima YousofiResearch Department and Review Cell, Altamash Institute of Dental Medicine, Karachi, Pakistan.
Afsheen MaqsoodDepartment of Oral Pathology, Bahria University Dental College, Karachi, Pakistan.
Sara AltamashDepartment of Orthodontics, Altamash Institute of Dental Medicine, Karachi, Pakistan.
Abhishek LalDepartment of Prosthodontics, Altamash Institute of Dental Medicine, Karachi, Pakistan.
Zarak KhanDepartment of Prosthodontics, Altamash Institute of Dental Medicine, Karachi, Pakistan.
Naseer AhmedDepartment of Prosthodontics, Altamash Institute of Dental Medicine, Karachi, Pakistan.
Artak HeboyanDepartment of Prosthodontics, Faculty of Stomatology, Yerevan State Medical University after Mkhitar Heratsi, Yerevan, Armenia.ORCID https://orcid.org/0000-0001-8329-3205
Karachi Medical and Dental College · PKBahria University · PKYerevan State Medical University · AM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this study was to assess the effectiveness of triamcinolone in combination with pentoxifylline and vitamin E in the treatment of patients with level two and three oral submucous fibrosis. Methods: The study aimed to compare the efficacy of corticosteroid injections (triamcinolone) versus pentoxifylline and vitamin E in the therapy of patients with stage two and three oral submucous fibrosis. A total of 42 participants with indications and features of oral submucous fibrosis were enrolled between January 2020 and September 2021. The patients' age and mouth opening were evaluated, and descriptive statistics and paired Results: The study showed a statistically significant improvement in both treatment groups ( Conclusions: The findings indicate that a treatment regimen combining pentoxifylline and triamcinolone can significantly alleviate oral submucous fibrosis symptoms, including mouth opening, pain, and flaring agitation, thereby enhancing the affected individual's quality of life.

Indexed as

oral submucosa fibrosispentoxifyllineTriamcinolonetumorvitamin E

Identifiers

PMID37786898
PMCPMC10541733
OpenAlexW4387195810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.