Evidence map›Paper›PMID 37786897›Full record

ReviewSAGE open medicine2023

The effects of advanced maternal age on perinatal mortality in Ethiopia: A systematic review and meta-analysis.

Gemechu Gelan Bekele, Ephrem Yohannes Roga, Dajane Negesse Gonfa, Amare Tesfaye Yami, Daniel Belema Fekene, Wogene Daro Kabale

Open access · goldAbstract readReview
In one paragraph

Review in SAGE open medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gemechu Gelan BekeleDepartment of Midwifery, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.ORCID https://orcid.org/0000-0002-8476-5320
Ephrem Yohannes RogaDepartment of Midwifery, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.ORCID https://orcid.org/0000-0002-3448-8310
Dajane Negesse GonfaDepartment of Midwifery, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.ORCID https://orcid.org/0000-0001-7819-5504
Amare Tesfaye YamiDepartment of Midwifery, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.ORCID https://orcid.org/0000-0001-5901-1677
Daniel Belema FekeneDepartment of Midwifery, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.
Wogene Daro KabaleDepartment of Midwifery, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.ORCID https://orcid.org/0000-0001-6736-2805
Ambo University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pregnancy in women over the age of 35 years is considered advanced maternal age. The relationship between advanced maternal age and the risk of perinatal mortality is still controversial. As a result, this systematic review and meta-analysis were carried out to clarify the relationship between advanced maternal age and perinatal mortality in Ethiopia. Methods: The following electronic databases were used for this systematic review and meta-analysis: PubMed, Web of Science, Scopus, Science Direct, Google Scholar, HINARI, and African Journals Online up to March 2022. Addis Ababa, Gondor, and Jimma University research repositories were also searched. A random-effects model was used to pool study-specific odds ratios. Results: A total of 18 articles, including a total of 45,541 participants, were included in the meta-analysis. A total of 11 cross-sectional, 2 case-control, and 5 cohort studies were included. The overall pooled estimate indicates that women with advanced maternal age had a 1.58 higher risk of perinatal mortality compared to women in the younger age group (odds ratio = 1.58; 95% Confidence Interval: 1.13-2.03). The subgroup analysis also revealed that there were differences in the effect size as the geographical region differed. The result showed that the odd of perinatal mortality was highest in the Oromia region and lowest in the Southern Nations Nationalities and Peoples' Region. Conclusion: The overall pooled estimate indicates that women with advanced maternal age had a 1.58-fold higher risk of perinatal mortality. Even though this risk could also be increased with other comorbid diseases, it is important for healthcare providers and other concerned stakeholders to be aware of the increased risks associated with advanced maternal age and provide different intervention programs designed to create awareness and provide counseling services to couples who seek to have a child in their later ages about the risks of advanced maternal age pregnancy on perinatal mortality and other adverse pregnancy outcomes.

Indexed as

advanced maternal ageEthiopiaperinatal mortality

Identifiers

PMID37786897
PMCPMC10541735
OpenAlexW4387195551

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.