Evidence map›Paper›PMID 37786754›Full record

ReviewIbrain2023

Routes and methods of neural stem cells injection in cerebral ischemia.

Xing-Yu Yang, Xiao Zhang, Jun-Feng Cao, Mei Wu, Sheng-Yan Chen, Li Chen

Open access · goldAbstract readReview
In one paragraph

Review in Ibrain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xing-Yu YangSchool of Clinic Medicine Chengdu Medical College Chengdu Sichuan China.
Xiao ZhangSchool of Basic Medicine Chengdu Medical College Chengdu Sichuan China.
Jun-Feng CaoSchool of Clinic Medicine Chengdu Medical College Chengdu Sichuan China.
Mei WuSchool of Clinic Medicine Chengdu Medical College Chengdu Sichuan China.
Sheng-Yan ChenSchool of Clinic Medicine Chengdu Medical College Chengdu Sichuan China.
Li ChenInstitute of Neurological Disease, Translational Neuroscience Center, West China Hospital Sichuan University Chengdu Sichuan China.ORCID 0000-0001-8628-7708
Chengdu Medical College · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral ischemia is a serious cerebrovascular disease with the characteristics of high morbidity, disability, and mortality. Currently, stem cell therapy has been extensively applied to a wide range of diseases, including neurological disorders, autoimmune deficits, and other diseases. Transplantation therapy with neural stem cells (NSCs) is a very promising treatment method, which not only has anti-inflammatory, antiapoptotic, promoting angiogenesis, and neurogenesis effects, but also can improve some side effects related to thrombolytic therapy. NSCs treatment could exert protective effects in alleviating cerebral ischemia-induced brain damage and neurological dysfunctions. However, the different injection routes and doses of NSCs determine diverse therapeutic efficacy. This review mainly summarizes the various injection methods and injection effects of NSCs in cerebral ischemia, as well as proposes the existing problems and prospects of NSCs transplantation.

Indexed as

cerebral ischemiainjection dosesinjection routesneural stem cells

Identifiers

PMID37786754
PMCPMC10527797
OpenAlexW4385614682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.