Evidence map›Paper›PMID 37786701›Full record

ArticlebioRxiv : the preprint server for biology2023

Context-dependent hyperactivity in

Sureni H Sumathipala, Suha Khan, Robert A Kozol, Yoichi Araki, Sheyum Syed, Richard L Huganir, Julia E Dallman

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sureni H SumathipalaDepartment of Biology, University of Miami, Coral Gables, FL USA.
Suha KhanDepartment of Biology, University of Miami, Coral Gables, FL USA.
Robert A KozolDepartment of Biology, University of Miami, Coral Gables, FL USA.
Yoichi ArakiDepartment of Neuroscience and Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine, Baltimore, MD USA.
Sheyum SyedDepartment of Physics, University of Miami, Coral Gables, FL USA.
Richard L HuganirDepartment of Neuroscience and Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine, Baltimore, MD USA.
Julia E DallmanDepartment of Biology, University of Miami, Coral Gables, FL USA.
University of Miami · USJohns Hopkins University · USNorth Carolina State University · US

Funding

Characterization of SynGAP Mutations in Human Cognitive DisordersR01MH112151 · NIMH · JOHNS HOPKINS UNIVERSITY · PI HUGANIR, RICHARD L · 2017 to 2021
$2.7M
Gastrointestinal Comorbidities in Autism Spectrum DisordersR21HD093021 · NICHD · UNIVERSITY OF MIAMI CORAL GABLES · PI DALLMAN, JULIA EVE · 2018 to 2019
$403k
Stable Zebrafish Models of Autism Spectrum DisorderR03MH103857 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI DALLMAN, JULIA EVE · 2014 to 2015
$151k
NICHD NIH HHS R21 HD093021NIMH NIH HHS R01 MH112151NIMH NIH HHS R03 MH103857
6 · The paper itself

Abstract

Background and Aims: SYNGAP1 disorder is a prevalent genetic form of Autism Spectrum Disorder and Intellectual Disability (ASD/ID) and is caused by Methods: We used CRISPR/Cas9 to introduce frameshift mutations in the Results: We show that CRISPR/Cas9 indels in zebrafish Conclusions: Our data support mutations in zebrafish

Identifiers

PMID37786701
PMCPMC10541574
OpenAlexW4386964711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.