ArticleBioinformatics advances2023
QuTIE: quantum optimization for target identification by enzymes.
Article in Bioinformatics advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
3 authors.
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Abstract
Summary: Target identification by enzymes (TIE) problem aims to identify the set of enzymes in a given metabolic network, such that their inhibition eliminates a given set of target compounds associated with a disease while incurring minimum damage to the rest of the compounds. This is a NP-hard problem, and thus optimal solutions using classical computers fail to scale to large metabolic networks. In this article, we develop the first quantum optimization solution, called Availability and implementation: Code and sample data are available at: https://github.com/ngominhhoang/Quantum-Target-Identification-by-Enzymes.
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Registered trials
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