Evidence map›Paper›PMID 37786426›Full record

ArticleClinical interventions in aging2023

Prognostic Value of Myocardial Function Imaging Markers in Elderly Patients Undergoing Transcatheter Aortic Valve Replacement.

Alexandra Dadarlat-Pop, Adrian Molnar, Adela Serban, Raluca Tomoaia, Claudia Hagiu, Simona Manole, Alexandru Oprea, Lorena Mocanu, Andrei Picos, Stefan Mot

Abstract read
In one paragraph

Article in Clinical interventions in aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexandra Dadarlat-PopCardiology Department, Heart Institute Niculae Stăncioiu, Cluj-Napoca, Romania.ORCID 0000-0003-3964-6995
Adrian Molnar *Cardiovascular Surgery Department, Heart Institute Niculae Stăncioiu, Cluj-Napoca, Romania.
Adela Serban *Cardiology Department, Heart Institute Niculae Stăncioiu, Cluj-Napoca, Romania.ORCID 0000-0001-7457-5753
Raluca TomoaiaCardiology Department, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Claudia Hagiu *Gastroenterology Department, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Simona Manole *Radiology and Medical Imaging Department, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.ORCID 0000-0002-8492-5777
Alexandru Oprea *Cardiovascular Surgery Department, Heart Institute Niculae Stăncioiu, Cluj-Napoca, Romania.ORCID 0000-0002-7686-7378
Lorena MocanuCardiology Department, Heart Institute Niculae Stăncioiu, Cluj-Napoca, Romania.
Andrei Picos *Department of Prevention in Dental Medicine, 'Iuliu Hatieganu' University of Medicine and Pharmacy, Cluj-Napoca, Romania.ORCID 0009-0002-6829-2559
Stefan MotCardiology Department, Heart Institute Niculae Stăncioiu, Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcatheter aortic valve replacement (TAVR) became the leading therapeutic strategy for aortic valve replacement in older patients with severe symptomatic aortic stenosis. Echocardiographic parameters that mark the left ventricle and right ventricle reverse remodeling after the TAVR are not well established. The aim of the current study is to describe the dynamics of both left ventricle (LV) and right ventricle (RV) strain derived from speckle tracking echocardiography in elderly patients at 3-months after the TAVR procedure. Methods: We enrolled 52 consecutive patients (77 ± 4.9 years old, median STS score of 3.1) who underwent transfemoral TAVR at our tertiary care center. All patients were evaluated at baseline and 3 months following TAVR. Results: The LV global longitudinal strain (GLS) 3-month following TAVR was significantly improved compared with baseline values (-16 ±4.2% vs -16 ±4.2%; p < 0.001) but no significant changes in the RV GLS 3 and 6 segments model following TAVR were registered. The LV ejection fraction was significantly improved 3-months after the TAVR procedure. LV-GLS at baseline demonstrated a strong positive correlation with LV-GLS at 3 months (r = 0.69) and a moderate correlation with RV strain parameters (r = 0.38 and r = 0.56), but also a negative correlation with LVEF at follow-up (r=-0.61). Interestingly, in contrast to LVEF, none of the strain parameters correlated with age. NT-proBNP values were correlated with both LV-GLS (r = 0.37) and LVEF (r=-0.5) at baseline. However, at follow-up, baseline NT-proBNP values remained correlated only to LV-GLS at 3-months (r = 0.24), but the correlation was weak.

Indexed as

Aortic Valve StenosisTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic ValveHumansPrognosisRetrospective StudiesStroke VolumeTreatment OutcomeVentricular Function, Leftaortic stenosiselderly populationglobal longitudinal strainoutcometranscatheter aortic valve replacement

Identifiers

PMID37786426
PMCPMC10541530

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.