Evidence map›Paper›PMID 37786246›Full record

Trial reportMedical science monitor : international medical journal of experimental and clinical research2023

Evaluating the Efficacy of Platelet-Rich Fibrin Matrix versus Subepithelial Connective Tissue Grafts in Dental Root Coverage: A Comparative Study Using Modified Ruben's Technique.

Justina P Louis, Jasmine M Crena, P S G Prakash, Sangeetha Subramanian, Dhayanand John Victor, Thodur Madapusi Balaji, Bassam Zidane, Manea Musa Musleh Al-Ahmari, Nassreen H Albar, Manea Musa Musleh Alahmari and 4 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medical science monitor : international medical journal of experimental and clinical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Justina P LouisDepartment of Periodontics, SRM Dental College, Ramapuram, Chennai, India.
Jasmine M CrenaDepartment of Periodontics, SRM Dental College, Chennai, India.ORCID 0000-0001-9788-3898
P S G PrakashDepartment of Periodontics, SRM Dental College, Chennai, India.ORCID 0000-0003-4243-5865
Sangeetha SubramanianDepartment of Periodontics, SRM Dental College, Chennai, India.ORCID 0000-0002-9352-6081
Dhayanand John VictorDepartment of Periodontics, SRM Dental College, Chennai, India.ORCID 0000-0002-1631-6427
Thodur Madapusi BalajiDepartment of Dentistry, Bharathiraja Hospital, Chennai, India.
Bassam ZidaneDepartment of Restorative Dentistry, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
Manea Musa Musleh Al-AhmariDepartment of Periodontics and Community Medical Science, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Nassreen H AlbarDivision of Operative Dentistry, Department of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
Manea Musa Musleh AlahmariDepartment of Periodontics and Community Medical Science, King Khalid University, Abha, Saudi Arabia.
Ibrahim F HalawaniDepartment of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.
Khalid J AlzahraniDepartment of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.ORCID 0000-0002-6688-0106
Abdullah F HalawaniDepartment of Biochemistry, King Faisal Hospital, Ministry of Health, Makkah, Saudi Arabia.
Shankargouda PatilCollege of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Dental root coverage, crucial in managing gingival recessions, traditionally utilizes subepithelial connective tissue grafts. However, this approach has limitations such as donor site morbidity and graft availability. Recent studies have introduced platelet-rich fibrin (PRF) as an alternative, leveraging its regenerative potential and growth factors. Despite the promise, comparative assessments between PRF and conventional grafts remain limited. This research probes whether PRF, when used beneath a modified Ruben's mixed flap, could provide comparable or superior dental root coverage than a subepithelial connective tissue graft. MATERIAL AND METHODS We enrolled 30 patients exhibiting Miller's class I and II recession in this comparative case series. Patients were randomly assigned to receive either a connective tissue graft (15 patients) or a PRF matrix (15 patients), both covered by a modified Ruben's mixed flap. RESULTS Clinical parameters, including full mouth plaque scores, bleeding scores, probing sulcus depth, clinical attachment level, gingival position assessment, width, and thickness of attached gingiva, were assessed in both the control and test groups at baseline, 6 months, and 12 months post-surgery. Significant differences were observed at all intervals.At the 12-month mark, the control group (connective tissue graft) achieved 91% complete root coverage, while the test group (PRF matrix) achieved 86%. However, this difference was not statistically significant. CONCLUSIONS The study outcomes suggest comparable gains in root coverage and attached gingiva between the connective tissue graft and PRF matrix groups. Thus, the results support our hypothesis that a subepithelial PRF matrix can serve as a viable alternative to a subepithelial connective tissue graft for treating dental root coverage.

Indexed as

Gingival RecessionPlatelet-Rich FibrinConnective TissueGingivaHumansOrganometallic CompoundsTooth RootTreatment OutcomeOrganometallic CompoundsRuthenium Ben

Identifiers

PMID37786246
PMCPMC10559832

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.