Evidence map›Paper›PMID 37783878›Full record

ArticleJournal of neuro-oncology2023

Supramaximal resection based on en-bloc technique reduces tumor burden and prolongs survival in primary supratentorial lobar glioblastoma.

Tianshi Que, Guanglong Huang, Jian-Er Tan, Peidong Zhang, Zhiyong Li, Guozhong Yi, Haojie Zheng, Xi Yuan, Xiang Xiao, Junlu Liu and 3 more

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In one paragraph

Article in Journal of neuro-oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Tianshi QueDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Guanglong HuangDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Jian-Er TanNanfang PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Peidong ZhangDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Zhiyong LiDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Guozhong YiDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Haojie ZhengDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Xi YuanDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Xiang XiaoDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Junlu LiuDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Haiyan XuDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Xi-An ZhangDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. zxa@smu.edu.cn.
Songtao QiDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China. qisongtaonfyy@126.com.
Nanfang Hospital · CNSouthern Medical University · CN

Funding

Clinical Research Program of Nanfang Hospital 2020CR017National Natural Science Foundation of China 81702473National Natural Science Foundation of China 82102100Natural Science Foundation of Guangdong Province 2114050002642President Fund of Nanfang Hospital 2018Z015
6 · The paper itself

Abstract

purposeResection beyond the contrast-enhanced zone contributed to reduce tumor burden and prolong survival in glioblastomas. The optimal extent of resection (EOR) and how to achieve it are worthy of continuous investigation for obtaining a satisfactory balance between maximal resection and the preservation of neurological function.

methodsA total of 340 adult supratentorial lobar glioblastomas (included astrocytoma, WHO 4, IDH mutation and glioblastoma) were retrospectively evaluated. The clinical data, EOR, technique of resection, postoperative complications, overall survival (OS) and progression-free survival (PFS) were assessed by univariate, multivariate and propensity score matched analysis. Histological staining was performed to comprehend the effect of the membranous structures and the cell distribution in tumoral and peritumoral regions.

resultsSupramaximal resection (SMR) was confirmed as resection with 100% EOR

conclusionsApplying en-bloc technique and achieving SMR, which could reduce tumor burden and did not increase additional complications, both had remarkedly positive effects on clinical outcomes in patients with primary supratentorial lobar glioblastomas.

Indexed as

AstrocytomaBrain NeoplasmsGlioblastomaSupratentorial NeoplasmsAdultHumansMiddle AgedNeurosurgical ProceduresRetrospective StudiesTreatment OutcomeTumor BurdenClinical outcomesEn-bloc techniqueGlioblastomaMembranous structuresSupramaximal resection

Identifiers

PMID37783878
OpenAlexW4387294011

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.