Evidence map›Paper›PMID 37783861›Full record

ArticleAAPS PharmSciTech2023

Polymeric Nanocapsules Containing Ozonated Oil and Terbinafine Hydrochloride as a Potential Treatment Against Dermatophytes.

Francielli Lima Dos Santos, Júlia Capp Zilles, Andressa Urbano Machado, Morgana Souza Marques, Bárbara Souza da Costa, Irene Clemes Kulkamp Guerreiro, Alexandre Meneghello Fuentefria, Renata Vidor Contri

Abstract read
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In one paragraph

Article in AAPS PharmSciTech, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Francielli Lima Dos SantosFaculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga, 2752, Azenha, Porto Alegre, RS, 90610-000, Brazil.
Júlia Capp ZillesPrograma de Pós-Graduação em Ciências Farmacêuticas - PPGCF, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, 90610-000, Brazil.
Andressa Urbano MachadoFaculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga, 2752, Azenha, Porto Alegre, RS, 90610-000, Brazil.
Morgana Souza MarquesPrograma de Pós-Graduação em Ciências Farmacêuticas - PPGCF, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, 90610-000, Brazil.
Bárbara Souza da CostaPrograma de Pós-Graduação em Ciências Farmacêuticas - PPGCF, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, 90610-000, Brazil.
Irene Clemes Kulkamp GuerreiroFaculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga, 2752, Azenha, Porto Alegre, RS, 90610-000, Brazil.
Alexandre Meneghello FuentefriaFaculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga, 2752, Azenha, Porto Alegre, RS, 90610-000, Brazil.
Renata Vidor ContriFaculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga, 2752, Azenha, Porto Alegre, RS, 90610-000, Brazil. renata.contri@ufrgs.br.ORCID http://orcid.org/0000-0002-0141-0808
Universidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Terbinafine hydrochloride is a synthetic allylamine whose mechanism of action consists of inhibiting the enzyme squalene epoxidase that participates in the first stage of ergosterol synthesis, interfering with fungal membrane function. Ozonated oils are used for topical application of ozone, producing reactive oxygen species that cause cellular damage in microorganisms, therefore being an alternative treatment for acute and chronic skin infections. This study aimed to develop and characterize Eudragit

Indexed as

ArthrodermataceaeNanocapsulesAntifungal AgentsOilsTerbinafineAntifungal AgentsNanocapsulesOilsTerbinafinedermatophytosisozonated oilpolymeric nanocapsulesskinterbinafine hydrochloride

Identifiers

PMID37783861
OpenAlexW4387245964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.